ArticleCancer epidemiology2014
Birth weight and subsequent risk of cancer.
Article in Cancer epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Early-life anthropometry and colorectal cancer risk in adulthood: Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis of prospective studies.International journal of cancer · 2025Pooled it
- Birth characteristics and risk of colorectal cancer.BMC gastroenterology · 2024Pooled it
- Association of birth weight with cancer risk: a dose-response meta-analysis and Mendelian randomization study.Journal of cancer research and clinical oncology · 2023Pooled it
- Birth Weight and Subsequent Risk of Total Leukemia and Acute Leukemia: A Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2021Pooled it
- Association of maternal thyroid function with birthweight: a systematic review and individual-participant data meta-analysis.The lancet. Diabetes & endocrinology · 2020Pooled it
- Association of high birth weight with risk of early-onset colorectal cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Early and late-onset colorectal cancers: a case-case comparison of risk factors.Cancer causes & control : CCC · 2026Article
- Article
- Constitutional Epimutations: From Rare Events Toward Major Cancer Risk Factors?JCO precision oncology · 2025Review
- Causal effect of life-course adiposity on the risk of respiratory diseases: a Mendelian randomization study.Nutrition & metabolism · 2025Article
- Associations between birthweight and preterm birth and the ages at menarche and menopause.BMC women's health · 2024Article
- Disentangling the link between maternal influences on birth weight and disease risk in 36,211 genotyped mother-child pairs.Communications biology · 2024Article
- Changing epidemiology of colorectal cancer - birth cohort effects and emerging risk factors.Nature reviews. Gastroenterology & hepatology · 2024Review
- Birthweight, genetic risk, and gastrointestinal cancer incidence: a prospective cohort study.Annals of medicine · 2023Article
- Causal effects of time-varying body size on selected autoimmune disorders: a life course Mendelian randomisation study.RMD open · 2023Observational
- Preterm birth, birthweight, and subsequent risk for depression.Journal of developmental origins of health and disease · 2023Article
- Association of maternal birth weight and maternal preterm birth with subsequent risk for adverse reproductive outcomes: The Women's Health Initiative.Early human development · 2023Article
- Associations of maternal preterm birth with subsequent risk for type 2 diabetes in women from the women's health initiative.Journal of developmental origins of health and disease · 2023Article
- Review of mendelian randomization studies on age at natural menopause.Frontiers in endocrinology · 2023Review
- The Association of Self-Reported Birthweight with Lung Function and Respiratory Diseases: Results from a Multi-Centre, Multi-Case Control Study in Italy.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
backgroundWe aimed to determine the association between self-reported birth weight and incident cancer in the Women's Health Initiative Observational Study cohort, a large multiethnic cohort of postmenopausal women.
methods65,850 women reported their birth weight by category (<6 lbs, 6-7 lbs 15 oz, 8-9 lbs 15 oz, and ≥10 lbs). All self-reported, incident cancers were adjudicated by study staff. We used Cox proportional hazards regression to estimate crude and adjusted hazard ratios (aHR) for associations between birth weight and: (1) all cancer sites combined, (2) gynecologic cancers, and (3) several site-specific cancer sites.
resultsAfter adjustments, birth weight was positively associated with the risk of lung cancer (p=0.01), and colon cancer (p=0.04). An inverse trend was observed between birth weight and risk for leukemia (p=0.04). A significant trend was not observed with breast cancer risk (p=0.67); however, women born weighing ≥10 lbs were less likely to develop breast cancer compared to women born between 6 lbs-7 lbs 15 oz (aHR 0.77, 95% CI 0.63, 0.94).
conclusionBirth weight category appears to be significantly associated with the risk of any postmenopausal incident cancer, though the direction of the association varies by cancer type.
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