Aging of the hematopoietic stem cells niche.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

20 citing papers in PubMed.

1. Impaired formation of erythroblastic islands is associated with erythroid failure and poor prognosis in a significant proportion of patients with myelodysplastic syndromes.Haematologica · 2016
   Trial
2. Combination Therapy of Losartan and Fisetin Reduces Senescence and Enhances Osteogenesis in Human Bone Marrow-Derived Mesenchymal Stem Cells.Journal of tissue engineering and regenerative medicine · 2025
   Article
3. Bone marrow adipocytes: key players in vascular niches, aging, and disease.Frontiers in cell and developmental biology · 2025
   Review
4. Reducing functionally defective old HSCs alleviates aging-related phenotypes in old recipient mice.Cell research · 2025
   Article
5. Hematopoietic stem cell size heterogeneity is not linked to changes in stem cell potential of aged HSCs.Frontiers in aging · 2025
   Article
6. Is Myelodysplasia a Consequence of Normal Aging?Current oncology reports · 2021
   Review
7. Cellular senescence in lymphoid organs and immunosenescence.Aging · 2021
   Review
8. Hematopoietic stem cell stretches and moves in its bone marrow niche.Critical reviews in oncology/hematology · 2021
   Review
9. Molecular and cellular mechanisms of aging in hematopoietic stem cells and their niches.Journal of hematology & oncology · 2020
   Review
10. Haematopoietic stem cell activity and interactions with the niche.Nature reviews. Molecular cell biology · 2019
    Review
11. Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline.Nature communications · 2018
    Article
12. Aging alters the epigenetic asymmetry of HSC division.PLoS biology · 2018
    Article
13. TGF-β Signaling Accelerates Senescence of Human Bone-Derived CD271 and SSEA-4 Double-Positive Mesenchymal Stromal Cells.Stem cell reports · 2018
    Article
14. Adipocytes role in the bone marrow niche.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2018
    Article
15. The hematopoietic stem cell niche: from embryo to adult.Development (Cambridge, England) · 2018
    Review
16. Immune senescence: significance of the stromal microenvironment.Clinical and experimental immunology · 2017
    Review
17. Guest editorial: Cooperative networks for stem cell homeostasis in normal and malignant hematopoiesis: from metabolism to epigenetics.International journal of hematology · 2016
    Article
18. Systemic Problems: A perspective on stem cell aging and rejuvenation.Aging · 2015
    Review
19. The importance of hypoxia and extra physiologic oxygen shock/stress for collection and processing of stem and progenitor cells to understand true physiology/pathology of these cells ex vivo.Current opinion in hematology · 2015
    Review
20. Histoarchitectural Deterioration of Lymphoid Tissues in HIV-1 Infection and in Aging.AIDS research and human retroviruses
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as