SynthesisTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2014
Nonoccupational physical activity and risk of ovarian cancer: a meta-analysis.
Synthesis in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 5 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Physical activity, sedentary behavior and ovarian cancer risk in Asian populations: a scoping review and meta-analysis.BMC cancer · 2026Pooled it
- Association between physical activity and gynecological cancers: a meta-analysis of prospective cohort studies.BMC women's health · 2025Pooled it
- Association between dietary fiber intake and risk of ovarian cancer: a meta-analysis of observational studies.The Journal of international medical research · 2018Pooled it
- Household physical activity and cancer risk: a systematic review and dose-response meta-analysis of epidemiological studies.Scientific reports · 2015Pooled it
- Prognostic Value of MicroRNA-182 in Cancers: A Meta-Analysis.Disease markers · 2015Pooled it
- Regular Physical Inactivity and Ovarian Cancer Risk in the Ovarian Cancer in Women of African Ancestry Consortium.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Review
- Development and Evaluation of an Accelerometer-Based Protocol for Measuring Physical Activity Levels in Cancer Survivors: Development and Usability Study.JMIR mHealth and uHealth · 2020Article
- American College of Sports Medicine Roundtable Report on Physical Activity, Sedentary Behavior, and Cancer Prevention and Control.Medicine and science in sports and exercise · 2019Review
- An Executive Summary of Reports from an International Multidisciplinary Roundtable on Exercise and Cancer: Evidence, Guidelines, and Implementation.Rehabilitation oncology (American Physical Therapy Association. Oncology Section) · 2019Article
- Associations of a Healthy Lifestyle Index With the Risks of Endometrial and Ovarian Cancer Among Women in the Women's Health Initiative Study.American journal of epidemiology · 2019Article
- Preventable fractions of colon and breast cancers by increasing physical activity in Brazil: perspectives from plausible counterfactual scenarios.Cancer epidemiology · 2018Article
- Chronic Recreational Physical Inactivity and Epithelial Ovarian Cancer Risk: Evidence from the Ovarian Cancer Association Consortium.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016Review
- Recreational physical activity and ovarian cancer risk in African American women.Cancer medicine · 2016Article
- A prospective study of leisure-time physical activity and risk of incident epithelial ovarian cancer: Impact by menopausal status.International journal of cancer · 2016Article
- Lifestyle changes and the risk of developing endometrial and ovarian cancers: opportunities for prevention and management.International journal of women's health · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies concerning the association between nonoccupational physical activity (PA) and risk of ovarian cancer yielded mixed results. We investigated the association by performing a meta-analysis. Relevant studies were identified by searching PubMed and EMBASE to June 2014. We calculated the summary relative risks (RRs) and 95% confidence intervals (CIs) using random-effects models. The dose-response relationship was assessed by restricted cubic spline model and multivariate random-effect meta-regression. Nine cohort studies and ten case-control studies involving 730,703 participants and 9,459 cases of ovarian cancer were selected for meta-analysis. The analyses showed that individuals who participated in any amount of nonoccupational PA had a RR of 0.92 (95% CI = 0.84-1.00) for risk of ovarian cancer. Those who participated in high or moderate nonoccupational PA had a RR of ovarian cancer risk of 0.89 (95% CI = 0.79-1.01) and 0.91 (95% CI = 0.85-0.99), respectively. Stratifying by study design and cancer subtype (borderline and invasive tumors), inverse association was only found in case-control studies. A linear but not significant dose-response relationship was found between nonoccupational PA and ovarian cancer risk. In conclusion, a weak inverse association exists between nonoccupational PA and the risk of ovarian cancer. Regarding the significant heterogeneity among included studies, confirmation in further prospective cohort studies with more accurate assessment of PA level is essential.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.