Evidence map›Paper›PMID 25093987›Full record

ArticleMolecules (Basel, Switzerland)2014

Influence of vinegar and wine processing on the alkaloid content and composition of the traditional Chinese medicine Corydalis Rhizoma (Yanhusuo).

Hongwei Wu, Katharina Waldbauer, Liying Tang, Lianwu Xie, Ruxandra McKinnon, Martin Zehl, Hongjun Yang, Haiyu Xu, Brigitte Kopp

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Unlocking the Hepatoprotective Potential ofFood science & nutrition · 2026
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  5. Processing and Compatibility ofEvidence-based complementary and alternative medicine : eCAM · 2021
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  6. Rapid Quality Identification of Decoction Pieces of Crude and ProcessedJournal of analytical methods in chemistry · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Effects of processing adjuvants on traditional Chinese herbs.Journal of food and drug analysis · 2018
    Review
  15. Article
  16. Bioactive Compounds in Cornelian Cherry Vinegars.Molecules (Basel, Switzerland) · 2018
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Hongwei WuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Dong Nei Nan Xiao Jie 16, Beijing 100700, China.
Katharina WaldbauerDepartment of Pharmacognosy, University of Vienna, Althanstrasse 14, Vienna A-1090, Austria.
Liying TangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Dong Nei Nan Xiao Jie 16, Beijing 100700, China.
Lianwu XieCollege of Sciences, Central South University of Forestry and Technology, 498 South Shaoshan Road, Changsha 410004, China.
Ruxandra McKinnonDepartment of Pharmacognosy, University of Vienna, Althanstrasse 14, Vienna A-1090, Austria. ruxandra.mckinnon@univie.ac.at.
Martin ZehlDepartment of Pharmacognosy, University of Vienna, Althanstrasse 14, Vienna A-1090, Austria.
Hongjun YangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Dong Nei Nan Xiao Jie 16, Beijing 100700, China.
Haiyu XuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Dong Nei Nan Xiao Jie 16, Beijing 100700, China.
Brigitte KoppDepartment of Pharmacognosy, University of Vienna, Althanstrasse 14, Vienna A-1090, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corydalis Rhizoma is the dried tuber of Corydalis yanhusuo W.T. Wang which is used in traditional Chinese medicine for pain relief and blood activation. Before being used in the clinics, C. yanhusuo is traditionally processed through dry-frying or frying with vinegar, wine or salt. In this study, eleven alkaloids from Corydalis Rhizoma, namely protopine (1), α-allocryptopine (2), tetrahydrocolumbamine (3), coptisine (4), palmatine (5), berberine (6), dehydrocorydaline (7), D,L-tetrahydropalmatine (8), tetrahydroberberine (9), corydaline (10) and tetrahydrocoptisine (11) were simultaneously quantified using a newly developed high performance liquid chromatography-diode array detector (HPLC-DAD) method. The influence of vinegar and wine processing on the content of the main alkaloids of Corydalis Rhizoma was investigated. For this purpose, two common formulations with clinical application, namely the water decoction of Corydalis Rhizoma and its formula Jin Ling Zi San (combination of Corydalis Rhizoma and Toosendan Fructus) were studied. In the two water decoctions, wine and vinegar processing increased the amount of tertiary alkaloids. The differences were more pronounced for Jin Ling Zi San, in which case the content of all tertiary alkaloids (compounds 1, 2, 3, 8, 9, 10, 11) was increased by wine processing.

Indexed as

WineAcetic AcidAlkaloidsCorydalisDrugs, Chinese HerbalMedicine, Chinese TraditionalMetabolomicsMolecular StructurePlant ExtractsReproducibility of ResultsSolventsAcetic AcidAlkaloidsDrugs, Chinese HerbalPlant ExtractsSolvents

Identifiers

PMID25093987
PMCPMC6271193

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.