Evidence map›Paper›PMID 25093525›Full record

ArticleNature structural & molecular biology2014

SET-ting the stage for DNA repair.

Deepak K Jha, Sophia X Pfister, Timothy C Humphrey, Brian D Strahl

Abstract read
PubMed Publisher
In one paragraph

Article in Nature structural & molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. NSD2 as a Promising Target in Hematological Disorders.International journal of molecular sciences · 2022
    Review
  3. Review
  4. Review
  5. Review
  6. Histone lysine methyltransferases in biology and disease.Nature structural & molecular biology · 2019
    Review
  7. Article
  8. Transcription-associated events affecting genomic integrity.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Review
  9. Article
  10. Marked for death: targeting epigenetic changes in cancer.Nature reviews. Drug discovery · 2017
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deepak K JhaDepartment of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, North Carolina, USA.
Sophia X PfisterCancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Timothy C HumphreyCancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Brian D Strahl1] Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, North Carolina, USA. [2] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, North Carolina, USA.

Funding

Role of Set2 and H3 methylation in chromatin functionR01GM068088 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STRAHL, BRIAN D · 2003 to 2017
$3.4M
Medical Research Council MC_PC_12003NIGMS NIH HHS R01 GM068088
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA RepairDNA Breaks, Double-StrandedFungal ProteinsHistone-Lysine N-MethyltransferaseHistonesHumansProtein Processing, Post-TranslationalSaccharomycetalesSchizosaccharomycesFungal ProteinsH2AX protein, humanHistone-Lysine N-MethyltransferaseHistonesSETD2 protein, human

Identifiers

PMID25093525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.