ArticlePloS one2014
Characterisation of major histocompatibility complex class I in the Australian cane toad, Rhinella marina.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- The Amphibian Major Histocompatibility Complex-A Review and Future Outlook.Journal of molecular evolution · 2025Review
- Whole-mitogenome analysis unveils previously undescribed genetic diversity in cane toads across their invasion trajectory.Ecology and evolution · 2024Article
- Transcriptome annotation reveals minimal immunogenetic diversity among Wyoming toads,Conservation genetics (Print) · 2022Article
- Depauperate major histocompatibility complex variation in the endangered reticulated flatwoods salamander (Ambystoma bishopi).Immunogenetics · 2020Article
- A Glimpse of the Peptide Profile Presentation byJournal of immunology (Baltimore, Md. : 1950) · 2020Article
- Increased Adaptive Variation Despite Reduced Overall Genetic Diversity in a Rapidly Adapting Invader.Frontiers in genetics · 2019Article
- Article
- The things they carried: The pathogenic effects of old and new parasites following the intercontinental invasion of the Australian cane toad (International journal for parasitology. Parasites and wildlife · 2017Review
- ORIGINS AND GENETIC DIVERSITY OF INTRODUCED POPULATIONS OF THE PUERTO RICAN RED-EYED COQUÍ,Copeia · 2017Article
- Characterization of MHC class IA in the endangered southern corroboree frog.Immunogenetics · 2017Article
- Characterisation of major histocompatibility complex class I genes in Japanese Ranidae frogs.Immunogenetics · 2016Article
- Molecular characterization of MHC class II in the Australian invasive cane toad reveals multiple splice variants.Immunogenetics · 2016Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The Major Histocompatibility Complex (MHC) class I is a highly variable gene family that encodes cell-surface receptors vital for recognition of intracellular pathogens and initiation of immune responses. The MHC class I has yet to be characterised in bufonid toads (Order: Anura; Suborder: Neobatrachia; Family: Bufonidae), a large and diverse family of anurans. Here we describe the characterisation of a classical MHC class I gene in the Australian cane toad, Rhinella marina. From 25 individuals sampled from the Australian population, we found only 3 alleles at this classical class I locus. We also found large number of class I alpha 1 alleles, implying an expansion of class I loci in this species. The low classical class I genetic diversity is likely the result of repeated bottleneck events, which arose as a result of the cane toad's complex history of introductions as a biocontrol agent and its subsequent invasion across Australia.
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