ArticleJournal of nephropathology2014
Clinicopathological correlations in lupus nephritis; a single center experience.
Article in Journal of nephropathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Article
- Rapidly Progressive Lupus Nephritis With Concurrent Anti-GBM and ANCA Positivity: A Rare Case Report.Case reports in nephrology · 2025Article
- Clinicopathological Analysis and Its Correlation With Various Classes of Lupus Nephritis.Cureus · 2025Article
- Performance of Clinical and Biochemical Parameters in Identifying Renal Histopathology and Predictors of One-Year Renal Outcome in Lupus Nephritis-A Single Centre Study from India.Diagnostics (Basel, Switzerland) · 2022Article
- Spectrum of Morphological and Immunofluorescence Patterns in Lupus Nephritis: A Single Institutional Study.Cureus · 2022Article
- Melissa officinalis L: A Review Study With an Antioxidant Prospective.Journal of evidence-based complementary & alternative medicine · 2017Review
- Longitudinal assessment of monocyte chemoattractant protein-1 in lupus nephritis as a biomarker of disease activity.Clinical rheumatology · 2016Article
- Lupus nephritis in Bangladesh: unfolding the story.Journal of nephropharmacology · 2016Article
- Diabetes mellitus and renal failure: Prevention and management.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Review
- Modeling of the relationship between the environmental air pollution, clinical risk factors, and hospital mortality due to myocardial infarction in Isfahan, Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Article
- Spatial analysis of myocardial infarction in Iran: National report from the Iranian myocardial infarction registry.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Article
- Clinicopathological correlation in asian patients with biopsy-proven lupus nephritis.International journal of nephrology · 2015Article
- Predictive Factors of Hospital Mortality Due to Myocardial Infarction: A Multilevel Analysis of Iran's National Data.International journal of preventive medicine · 2015Article
- Systemic lupus erythematosus presenting with eye squinting: A rare association.Journal of translational internal medicineArticle
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRenal biopsies play an important role in the diagnosis, management and prognosis of patients with lupus nephritis (LN).
objectivesTo determine the correlation between the pathological features of LN and the demographic, clinical and laboratory parameters. PATIENTS AND
methodsThis retrospective study was conducted from 2008 to 2014 on all consecutive cases of biopsy-proven LN at a nephropathology laboratory in Iran. The demographic, clinical and laboratory data were obtained from patients(') files and the biopsy findings from the original biopsy request forms.
resultsOf the 84 patients enrolled, 69 (82.2%) were females and 15 (17.8%) males. The mean age was 32.7±12 years. The mean serum creatinine was 1.5±0.94 mg/dl and the mean 24-h proteinuria, 1.6±1.9 grams. The majority of cases belonged to classes III and IV. The extracapillary proliferation was found in 42.86% of biopsies and endocapillary proliferation in 66.67% of biopsies. Patients of class IV-LN had a higher mean serum value of creatinine in comparison to class III-LN (2.19±1.09 versus 1.2±0.56 mg/dl; p= 0.0001). There was no significant difference of 24-h proteinuria between the two classes (p= 0.882). A significant association of serum creatinine with 24-h proteinuria (p= 0.041) was seen. Serum creatinine had significant positive correlation with activity percent (p< 0.001), and chronicity percent (p= 0.006), and also with proportion of glomeruli with crescents (p < 0.001). While there was a significant relationship of proteinuria with chronicity percent (p= 0.001), this association for activity percent was not significant (p= 0.094). Furthermore, the association of proteinuria with totally sclerotic glomeruli and proportion of crescents was not statistically significant (p= 0.186 and p= 0.0145 respectively).
conclusionsIn conclusion, the results from our study on biopsy-proven cases of LN largely concur with the previously reported studies from Iran and other parts of the world.
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