Evidence map›Paper›PMID 25093103›Full record

ArticleJournal of thoracic disease2014

Myelomatous pleural effusion as an initial sign of multiple myeloma-a case report and review of literature.

Li-Li Zhang, Yuan-Yuan Li, Cheng-Ping Hu, Hua-Ping Yang

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of thoracic disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  3. Myelomatous Pleural Effusion: Thoracoscopic Findings.Internal medicine (Tokyo, Japan) · 2024
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  13. Flow Cytometry in Diagnosis of Myelomatous Pleural Effusion: A Case Report.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Li-Li ZhangDepartment of Respiratory & Critical Care Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Yuan-Yuan LiDepartment of Respiratory & Critical Care Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Cheng-Ping HuDepartment of Respiratory & Critical Care Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Hua-Ping YangDepartment of Respiratory & Critical Care Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDiscuss and improve the understanding of the clinical characters and diagnostic methods of myelomatous pleurisy, particularly of the patients with pleural effusion as an initial manifestation.

backgroundA 53-year-old male, who had been misdiagnosed as tuberculous pleurisy in a local hospital, was diagnosed as multiple myeloma (MM) with pleural infiltration. We reviewed the literature on clinical manifestations, serum and pleural effusion characters, treatment and diagnostic options of this exceptionally rare presentation of MM.

methodsWe conducted a search of the published medical literature since 2000 in MEDLINE and PubMed using search criteria [("pleural effusion" and "MM") or "myelomatous pleural effusions"]. The search led to 64 case reports, and 16 cases with pleural effusion as an initial manifestation were included in this review. We have also searched for recent advances in diagnosis. RESULTS AND

conclusionsMyelomatous pleurisy is a rare complication of MM. Its clinical and laboratory findings are non-specific. Definitive diagnosis relies on the histopathology of pleural biopsy or pleural effusion. Thoracoscopic pleural biopsy is reliable, safe and effective. Chemotherapy is the mainstay of treatment for myelomatous pleural effusion. However, the response rate is low with an overall median survival time of 4 months.

Indexed as

adenosine deaminase (ADA)extramedullary infiltrationMultiple myeloma (MM)myelomatous pleural effusionthoracoscope technology

Identifiers

PMID25093103
PMCPMC4120176
OpenAlexW2102783170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.