Evidence map›Paper›PMID 25092819›Full record

ArticleThe American journal of tropical medicine and hygiene2014

Serosurveillance of Orientia tsutsugamushi and Rickettsia typhi in Bangladesh.

Rapeephan R Maude, Richard J Maude, Aniruddha Ghose, M Robed Amin, M Belalul Islam, Mohammad Ali, M Shafiqul Bari, M Ishaque Majumder, Ampai Tanganuchitcharnchai, Arjen M Dondorp and 5 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03847870 (Background Seroprevalence of Rickettsial Infections in Myanmar), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03847870 completednot on this mapstarted 2019, after this paper: background citation

Background Seroprevalence of Rickettsial Infections in Myanmar

TypeobservationalSponsorMyanmar Oxford Clinical Research UnitRan2019 to 2019Enrolled700ConditionsRickettsiae InfectionsArmsMORU in-house ELISA test followed by IFA if positive
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Estimating the burden of scrub typhus: A systematic review.PLoS neglected tropical diseases · 2017
    Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Molecular characterization ofNew microbes and new infections · 2019
    Article
  17. Article
  18. Article
  19. Article
  20. A review of the global epidemiology of scrub typhus.PLoS neglected tropical diseases · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Rapeephan R Maude
Richard J Maude
Aniruddha Ghose
M Robed Amin
M Belalul Islam
Mohammad Ali
M Shafiqul Bari
M Ishaque Majumder
Ampai Tanganuchitcharnchai
Arjen M Dondorp
Daniel H Paris
Robin L Bailey
M Abul Faiz
Stuart D Blacksell
Nicholas P J Day
Churchill Hospital · GBMahidol Oxford Tropical Medicine Research Unit · THSir Salimullah Medical CollegeChittagong Medical College · BDComilla Medical College · BDLondon School of Hygiene & Tropical Medicine · GBMahidol University · THSylhet MAG Osmani Medical College · BD

Funding

Wellcome TrustWellcome Trust B9RPYY0
6 · The paper itself

Abstract

Scrub and murine typhus infections are under-diagnosed causes of febrile illness across the tropics, and it is not known how common they are in Bangladesh. We conducted a prospective seroepidemiologic survey across six major teaching hospitals in Bangladesh by using an IgM enzyme-linked immunosorbent assay. Results indicated recent exposure (287 of 1,209, 23.7% seropositive for Orientia tsutsugamushi and 805 of 1,209, 66.6% seropositive for Rickettsia typhi). Seropositive rates were different in each region. However, there was no geographic clustering of seropositive results for both organisms. There was no difference between those from rural or urban areas. Rickettsia typhi seroreactivity was positively correlated with age. Scrub typhus and murine typhus should be considered as possible causes of infection in Bangladesh.

Indexed as

AdultAntibodies, BacterialBangladeshEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin MMaleMiddle AgedOrientia tsutsugamushiProspective StudiesRickettsia typhiScrub TyphusSeroepidemiologic StudiesTyphus, Endemic Flea-BorneAntibodies, BacterialImmunoglobulin M

Identifiers

PMID25092819
PMCPMC4155564
OpenAlexW2152775336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.