ArticleEpilepsia2014
Epilepsy is ubiquitous, but more devastating in the poorer regions of the world... or is it?
Article in Epilepsia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Dravet syndrome: A systematic literature review of the illness burden.Epilepsia open · 2023Pooled it
- Depression among epileptic patients and its association with drug therapy in sub-Saharan Africa: A systematic review and meta-analysis.PloS one · 2019Pooled it
- Article
- The role of social context in cognitive and neurobehavioural outcomes in epilepsy.Nature reviews. Neurology · 2026Review
- Assistive Artificial Intelligence in Epilepsy and Its Impact on Epilepsy Care in Low- and Middle-Income Countries.Brain sciences · 2025Review
- Epilepsy in low- to middle-income countries.Current opinion in neurology · 2025Review
- Impact of hemispherotomy on quality of life and burden of caregivers in children and adolescents: a retrospective observational study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Observational
- Prevalence and Risk Factors of Epilepsy Among the Adult Saudi Population: A Systematic Review.Cureus · 2024Review
- Socio-demographic profiles and obstetrics outcomes of pregnant women with epilepsy in a vulnerability State, Brazil.PloS one · 2022Article
- Epilepsy inFrontiers in neurology · 2021Article
- The effect of Omaha System-based continuous nursing care on the psychological status, self-esteem, and quality of life in epileptic children.American journal of translational research · 2021Article
- Long-Term Impact of Single Epilepsy Training on Knowledge, Attitude and Practices: Comparison of Trained and Untrained Rwandan Community Health Workers.International journal of public health · 2021Article
- Late diagnosis of human immunodeficiency virus infection is linked to higher rates of epilepsy in children in the Eastern Cape of South Africa.Southern African journal of HIV medicine · 2020Article
- Bridging the childhood epilepsy treatment gap in northern Nigeria (BRIDGE): Rationale and design of pre-clinical trial studies.Contemporary clinical trials communications · 2019Article
- Clinico-etiological Profile and Developmental Status of Infants Aged 1-24 months with Epilepsy.Indian journal of pediatrics · 2019Article
- An ambispective cohort study on treatment outcomes of patients with epilepsy in a tertiary epilepsy center in Rwanda and recommendations for improved epilepsy care.Epilepsia open · 2019Article
- Review
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Authors and funding
3 authors at 3 institutions in 4 countries.
Funding
Abstract
The incidence and prevalence of active epilepsy are greatest in Africa compared to all other continents, even those with equivalent poor settings. This is a reflection of the high levels of structural and metabolic causes and may reflect an increased risk in parts of the continent. The full burden of epilepsy, which includes the social and medical morbidity of the disorder and where people with epilepsy are heavily stigmatized and frequently untreated, cannot be fully assessed even using the disability adjusted life-years, since the assigned disability weights are not specific to these regions. The burden is further exacerbated by social, geographic, and economic barriers to care and the inability of African health systems to manage people with epilepsy effectively because of lack of trained personnel, limited facilities, and poor access to effective or sustained supplies of antiepileptic drugs, or even therapy at all. The situation is compounded by a probable underestimation of the prevalence and incidence of people with epilepsy related to the major stigma associated with the condition in Africa, and the limited training available to most health care workers who are the primary point of assessing most people with epilepsy. Finding innovative ways to address the huge barriers faced by people with epilepsy in Africa needs to be a major goal for the millennium. A PowerPoint slide summarizing this article is available for download in the Supporting Information section here.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.