ArticleEuropean journal of nuclear medicine and molecular imaging2014
Use of diffusion-weighted imaging (DWI) in PET/MRI for head and neck cancer evaluation.
Article in European journal of nuclear medicine and molecular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic Performance of Whole-Body PET/MRI for Detecting Malignancies in Cancer Patients: A Meta-Analysis.PloS one · 2016Pooled it
- Positron Emission Tomography-Magnetic Resonance Imaging, a New Hybrid Imaging Modality for Dentomaxillofacial Malignancies-A Systematic Review.Diagnostics (Basel, Switzerland) · 2025Review
- PET/MRI: pictorial review of hepatobiliary and pancreatic applications.Abdominal radiology (New York) · 2025Review
- Role ofCancers · 2024Review
- The use of PET/MRI in radiotherapy.Insights into imaging · 2024Review
- International EANM-SNMMI-ISMRM consensus recommendation for PET/MRI in oncology.European journal of nuclear medicine and molecular imaging · 2023Article
- Article
- Prognostic value of 18F-FDG PET/MRI in patients with advanced oropharyngeal and hypopharyngeal squamous cell carcinoma.Annals of nuclear medicine · 2021Article
- Are Gadolinium-Enhanced MR Sequences Needed in SimultaneousAJNR. American journal of neuroradiology · 2020Article
- Response Evaluation of Choroidal Melanoma After Brachytherapy Using Diffusion-Weighted Magnetic Resonance Imaging (DW-MRI): Preliminary Findings.Frontiers in oncology · 2020Article
- Comparison ofEuropean journal of nuclear medicine and molecular imaging · 2020Article
- Clinical utility of simultaneous whole-bodyEuropean journal of nuclear medicine and molecular imaging · 2018Article
- Local recurrence of squamous cell carcinoma of the head and neck after radio(chemo)therapy: Diagnostic performance of FDG-PET/MRI with diffusion-weighted sequences.European radiology · 2018Article
- Diffusion magnetic resonance imaging: A molecular imaging tool caught between hope, hype and the real world of "personalized oncology".World journal of radiology · 2017Review
- FDG Whole-Body PET/MRI in Oncology: a Systematic Review.Nuclear medicine and molecular imaging · 2017Review
- Evaluation of PET/MRI for Tumor Volume Delineation for Head and Neck Cancer.Frontiers in oncology · 2017Article
- Optimized workflow and imaging protocols for whole-body oncologic PET/MRI.Japanese journal of radiology · 2016Article
- Transmission imaging for integrated PET-MR systems.Physics in medicine and biology · 2016Article
- [Molecular imaging of head and neck cancers : Perspectives of PET/MRI].Der Radiologe · 2016Review
- Combined multimodal co-registration of PET/CT and MRI images increases diagnostic accuracy in squamous cell carcinoma staging.La Radiologia medica · 2016Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to analyze whether diffusion-weighted imaging (DWI) adds significant information to positron emission tomography/magnetic resonance imaging (PET/MRI) on lesion detection and characterization in head and neck cancers.
methodsSeventy patients with different head and neck cancers were enrolled in this prospective study. All patients underwent sequential contrast-enhanced (ce) PET/computed tomography (CT) and cePET/MRI using a tri-modality PET/CT-MR setup either for staging or re-staging. First, the DWI alone was evaluated, followed by the PET/MRI with conventional sequences, and in a third step, the PET/MRI with DWI was evaluated. McNemar's test was used to evaluate differences in the accuracy of PET/MRI with and without DWI compared to the standard of reference.
resultsOne hundred eighty-eight (188) lesions were found, and of those, 118 (62.8%) were malignant and 70 (37.2%) were benign. PET/MRI without DWI had a higher accuracy in detecting malignant lesions than DWI alone (86.8% vs. 60.6%, p < 0.001). PET/MRI combined with DWI detected 120 concurrent lesions (89 malignant and 31 benign), PET/MRI alone identified 48 additional lesions (20 malignant and 28 benign), and DWI alone detected 20 different lesions (nine malignant and 11 benign). However, lesions detected on DWI did not change overall staging. SUV maximum and mean were significantly higher in malignant lesions than in benign lesions. DWI parameters between malignant and benign lesions were not statistically different.
conclusionThe use of DWI as part of PET/MRI to evaluate head and neck cancers does not provide remarkable information. Thus, the use of DWI might not be needed in clinical PET/MRI protocols for the staging or restaging of head and neck cancers.
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