Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2015
Preoperative nutritional support in cancer patients with no clinical signs of malnutrition--prospective randomized controlled trial.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 54 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Controlled Trial Comparing Postoperative Complication Between Preoperative Oral Nutritional Supplement With Dietary Advice and Conventional Dietary Advice Alone in Patients Undergoing Elective Major Gastrointestinal Surgery
Intensive Perioperative Nutrition Therapy
Who cites it
54 citing papers in PubMed, 11 syntheses or guidelines pooled it, 141 citations in OpenAlex.
- How Robust is the Evidence for Prehabilitation in Cancer Surgery?: A Systematic Review and Fragility Index Analysis.Annals of surgical oncology · 2026Pooled it
- Bridging the gap between prescription and participation: a systematic review and meta-analysis of factors influencing adherence to prehabilitation in gastrointestinal cancer surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Impact of Prehabilitation in Major Gastrointestinal Oncological Surgery: a Systematic Review.Journal of gastrointestinal cancer · 2025Pooled it
- Prehabilitation Outcomes in Surgical Oncology Patients Undergoing Major Abdominal Surgery: A Meta-analysis of Randomized Control Trials.Annals of surgical oncology · 2025Pooled it
- High-protein oral nutritional supplement use in patients with cancer reduces complications and length of hospital stay: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Experiences of cancer patients in receiving dietary advice from healthcare professionals and of healthcare professionals in providing this advice-a systematic review.Journal of cancer survivorship : research and practice · 2024Pooled it
- Preoperative nutrition therapy in people undergoing gastrointestinal surgery.The Cochrane database of systematic reviews · 2024Pooled it
- Nutrition as prevention for improved cancer health outcomes: a systematic literature review.JNCI cancer spectrum · 2023Pooled it
- Oral nutrition interventions in patients undergoing gastrointestinal surgery for cancer: A systematic literature review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Pooled it
- Effects of nutritional support on the clinical outcomes of well-nourished patients with cancer: a meta-analysis.European journal of clinical nutrition · 2020Pooled it
- Preoperative exercise therapy for gastrointestinal cancer patients: a systematic review.Systematic reviews · 2018Pooled it
- Trial
- Trial
- Exploring reasons behind patient compliance with nutrition supplements before pelvic exenteration surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Trial
- Low protein, high risk: hypoalbuminemia predicts adverse outcomes after mastectomy in 37,848 breast cancer patients.Breast cancer (Tokyo, Japan) · 2026Article
- Optimizing perioperative care in autologous breast reconstruction: a narrative review.Gland surgery · 2026Review
- Development of an artificial intelligence-based prediction platform for early recurrence of resectable pancreatic cancer after curative surgery-toward future use as an indication for neoadjuvant treatment: a retrospective multicenter cohort study.Annals of surgical treatment and research · 2026Article
- Prevalence of malnutrition and the appropriateness of nutritional support among patients with hematologic malignancies: a GLIM-based study.Frontiers in nutrition · 2026Article
- Preoperative C-reactive protein-augmented CONUT score as a better prognostic indicator than CONUT alone in non-small cell lung cancer across age groups.Journal of thoracic disease · 2025Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePreoperative nutrition is beneficial for malnourished cancer patients. Yet, there is little evidence whether or not it should be given to nonmalnourished patients. The aim of this study was to assess the need to introduce preoperative nutritional support in patients without malnutrition at qualification for surgery.
methodsThis was a prospective, two-arm, randomized, controlled, open-label study. Patients in interventional group received nutritional supplementation for 14 days before surgery, while control group kept on to their everyday diet. Each patient's nutritional status was assessed twice--at qualification (weight loss in 6 months, laboratory parameters: albumin, total protein, transferrin, and total lymphocyte count) and 1 day before surgery (change in body weight and laboratory parameters). After surgery, all patients were followed up for 30 days for postoperative complications.
resultsFifty-four patients in interventional and 48 in control group were analyzed. In postoperative period, patients in control group suffered from significantly higher (p < 0.001) number of serious complications compared with patients receiving nutritional supplementation. Moreover, levels of all laboratory parameters declined significantly (p < 0.001) in these patients, while in interventional arm were stable (albumin and total protein) or raised (transferrin and total lymphocyte count).
conclusionsPreoperative nutritional support should be introduced for nonmalnourished patients as it helps to maintain proper nutritional status and reduce number and severity of postoperative complications compared with patients without such support.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.