Evidence map›Paper›PMID 25090637›Full record

ArticlePolymer chemistry2014

Catch and Release: Photocleavable Cationic Diblock Copolymers as a Potential Platform for Nucleic Acid Delivery.

Matthew D Green, Abbygail A Foster, Chad T Greco, Raghunath Roy, Rachel M Lehr, Thomas H Epps, Millicent O Sullivan

Open access · hybridAbstract read
In one paragraph

Article in Polymer chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Technologies for controlled, local delivery of siRNA.Journal of controlled release : official journal of the Controlled Release Society · 2015
    Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Matthew D GreenDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA. ; Tel: +1 302 831 8072.
Abbygail A FosterDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA. ; Tel: +1 302 831 8072.
Chad T GrecoDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA. ; Tel: +1 302 831 8072.
Raghunath RoyDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA. ; Tel: +1 302 831 8072.
Rachel M LehrDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA. ; Tel: +1 302 831 8072.
Thomas H EppsDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA. ; Tel: +1 302 831 8072.
Millicent O SullivanDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE 19716, USA. ; Tel: +1 302 831 8072.
University of Delaware · US

Funding

Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI PATEL, SANDEEP · 2014 to 2018
$5.8M
Molecular Design of Advanced BiomaterialsP20GM103541 · NIGMS · UNIVERSITY OF DELAWARE · PI POLENOVA, TATYANA · 2012 to 2012
$2.1M
NIGMS NIH HHS P20 GM103541NIGMS NIH HHS P30 GM110758
6 · The paper itself

Abstract

Binding interactions between DNA and cationic carriers must be sufficiently strong to prevent nuclease-mediated degradation, yet weak enough to permit transcription. We demonstrate cationic diblock copolymers containing PEG and

Identifiers

PMID25090637
PMCPMC4115287
OpenAlexW1980899104

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.