ArticleOptics express2014
Architecture and applications of a high resolution gated SPAD image sensor.
Article in Optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- High-speed fluorescence lifetime imaging microscopy: techniques, applications, and prospects.Biophotonics discovery · 2025Review
- Time-Resolved Laser Speckle Contrast Imaging (TR-LSCI) of Cerebral Blood Flow.IEEE transactions on medical imaging · 2025Article
- Sequential analysis and its applications to neuromorphic engineering.Frontiers in neuroscience · 2025Article
- Towards measurements of absolute membrane potential in Bacillus subtilis using fluorescence lifetime.bioRxiv : the preprint server for biology · 2024Article
- Underwater Single-Photon 3D Reconstruction Algorithm Based on K-Nearest Neighbor.Sensors (Basel, Switzerland) · 2024Article
- Fluorescence Multi-Detection Device Using a Lensless Matrix Addressable microLED Array.Biosensors · 2024Article
- Light-sheet autofluorescence lifetime imaging with a single-photon avalanche diode array.Journal of biomedical optics · 2023Article
- Light sheet autofluorescence lifetime imaging with a single photon avalanche diode array.bioRxiv : the preprint server for biology · 2023Article
- Fast Gating for Raman Spectroscopy.Sensors (Basel, Switzerland) · 2021Review
- Article
- Fluorescence lifetime imaging with a megapixel SPAD camera and neural network lifetime estimation.Scientific reports · 2020Article
- Wide-field time-gated SPAD imager for phasor-based FLIM applications.Methods and applications in fluorescence · 2020Article
- Phasor-based widefield FLIM using a gated 512×512 single-photon SPAD imager.Proceedings of SPIE--the International Society for Optical Engineering · 2019Article
- Single-photon avalanche diode imagers in biophotonics: review and outlook.Light, science & applications · 2019Review
- Widefield High Frame Rate Single-Photon SPAD Imagers for SPIM-FCS.Biophysical journal · 2018Article
- Quantum-Optically Enhanced STORM (QUEST) for Multi-Emitter Localization.Scientific reports · 2018Article
- High Dynamic Range Imaging at the Quantum Limit with Single Photon Avalanche Diode-Based Image Sensors.Sensors (Basel, Switzerland) · 2018Article
- Recent Advances in Fluorescence Lifetime Analytical Microsystems: Contact Optics and CMOS Time-Resolved Electronics.Sensors (Basel, Switzerland) · 2017Review
- SPAD imagers for super resolution localization microscopy enable analysis of fast fluorophore blinking.Scientific reports · 2017Article
- Images from Bits: Non-Iterative Image Reconstruction for Quanta Image Sensors.Sensors (Basel, Switzerland) · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
We present the architecture and three applications of the largest resolution image sensor based on single-photon avalanche diodes (SPADs) published to date. The sensor, fabricated in a high-voltage CMOS process, has a resolution of 512 × 128 pixels and a pitch of 24 μm. The fill-factor of 5% can be increased to 30% with the use of microlenses. For precise control of the exposure and for time-resolved imaging, we use fast global gating signals to define exposure windows as small as 4 ns. The uniformity of the gate edges location is ∼140 ps (FWHM) over the whole array, while in-pixel digital counting enables frame rates as high as 156 kfps. Currently, our camera is used as a highly sensitive sensor with high temporal resolution, for applications ranging from fluorescence lifetime measurements to fluorescence correlation spectroscopy and generation of true random numbers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.