ReviewToxins2014
Quorum sensing in Bacillus thuringiensis is required for completion of a full infectious cycle in the insect.
Review in Toxins, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 98 citations in OpenAlex.
- FACS-based isolation and recovery of physiologically distinct bacterial subpopulations from infected insect hosts.MethodsX · 2026Article
- Review
- Integrated Genomic and Phenotypic Analysis ofMicroorganisms · 2025Article
- RRNPP quorum-sensing repertoires in the salivarius group genomes: overrepresentation and synchronous activation of SHP/Rgg systems inJournal of bacteriology · 2025Article
- Comparative genomics analysis of Bacillus altitudinis G03 provides insights into its biocontrol and probiotic traits.BMC genomics · 2025Article
- NupR Is Involved in the Control of PlcR: A Pleiotropic Regulator of Extracellular Virulence Factors.Microorganisms · 2025Article
- Exploring the Genomic Landscape ofCurrent issues in molecular biology · 2024Article
- Investigating the Role of OrbF in Biofilm Biosynthesis and Regulation of Biofilm-Associated Genes inFoods (Basel, Switzerland) · 2024Article
- The quorum-sensing peptidic inhibitor rescues host immune system eradication: A novel infectivity mechanism.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A Sporulation-Independent Way of Life for Bacillus thuringiensis in the Late Stages of an Infection.mBio · 2023Article
- From cereus to anthrax and back again: Assessment of the temperature-dependent phenotypic switching in the "cross-over" strainFrontiers in microbiology · 2023Article
- Computational tools for exploring peptide-membrane interactions in gram-positive bacteria.Computational and structural biotechnology journal · 2023Review
- Review
- The Fate of Bacteria of the Bacillus cereus Group in the Amoeba Environment.Microbial ecology · 2022Article
- Oral Immune Priming Treatment Alters Microbiome Composition in the Red Flour BeetleFrontiers in microbiology · 2022Article
- Adaptation of Bacillus thuringiensis to Plant Colonization Affects Differentiation and Toxicity.mSystems · 2021Article
- The Distribution of Several Genomic Virulence Determinants Does Not Corroborate the Established Serotyping Classification ofInternational journal of molecular sciences · 2021Article
- Unique inducible filamentous motility identified in pathogenic Bacillus cereus group species.The ISME journal · 2020Article
- The Alternative Sigma Factor SigB Is Required for the Pathogenicity of Bacillus thuringiensis.Journal of bacteriology · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial cell-cell communication or quorum sensing (QS) is a biological process commonly described as allowing bacteria belonging to a same pherotype to coordinate gene expression to cell density. In Gram-positive bacteria, cell-cell communication mainly relies on cytoplasmic sensors regulated by secreted and re-imported signaling peptides. The Bacillus quorum sensors Rap, NprR, and PlcR were previously identified as the first members of a new protein family called RNPP. Except for the Rap proteins, these RNPP regulators are transcription factors that directly regulate gene expression. QS regulates important biological functions in bacteria of the Bacillus cereus group. PlcR was first characterized as the main regulator of virulence in B. thuringiensis and B. cereus. More recently, the PlcR-like regulator PlcRa was characterized for its role in cysteine metabolism and in resistance to oxidative stress. The NprR regulator controls the necrotrophic properties allowing the bacteria to survive in the infected host. The Rap proteins negatively affect sporulation via their interaction with a phosphorelay protein involved in the activation of Spo0A, the master regulator of this differentiation pathway. In this review we aim at providing a complete picture of the QS systems that are sequentially activated during the lifecycle of B. cereus and B. thuringiensis in an insect model of infection.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.