ReviewThe Analyst2014
Enabling robust quantitative readout in an equipment-free model of device development.
Review in The Analyst, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- A field-deployable CRISPR-based biosensing platform for monitoring marine ecosystems.Nature sustainability · 2026Article
- Quantitative and equipment-free paper-based agglutination assay of bacterial cells.RSC advances · 2024Article
- Promise and perils of paper-based point-of-care nucleic acid detection for endemic and pandemic pathogens.Lab on a chip · 2023Review
- Tunable Duplex Semiquantitative Detection of Nucleic Acids with a Visual Lateral Flow Immunoassay Readout.Analytical chemistry · 2022Article
- Manipulating the hydrophobicity of DNA as a universal strategy for visual biosensing.Nature protocols · 2020Article
- An Open Software Platform for the Automated Design of Paper-Based Microfluidic Devices.Scientific reports · 2017Article
- Review
- Mechanical Fracturing of Core-Shell Undercooled Metal Particles for Heat-Free Soldering.Scientific reports · 2016Article
- Development of a Whole Blood Paper-Based Device for Phenylalanine Detection in the Context of PKU Therapy Monitoring.Micromachines · 2016Article
- Design, Synthesis, and Characterization of Small-Molecule Reagents That Cooperatively Provide Dual Readouts for Triaging and, When Necessary, Quantifying Point-of-Need Enzyme Assays.The Journal of organic chemistry · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
A critical constraint in the design of appropriate medical devices for the lowest-resource settings is the lack of access to maintenance or repair on instrumentation. There are numerous point-of-care applications for which quantitative readout would have clinical utility. Thus, a challenge to the device developer is to enable quantitative device readout in an equipment-free model that is appropriate for use in even the lowest-resource settings. Paper microfluidics has great potential for enabling equipment-free devices that are low-cost, operable by minimally-trained users, and provide quantitative readout. The focus of this critical review is to describe the work, starting several decades ago and continuing to the present, to enable assays with quantitative readout in a fully-disposable device.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.