ArticleMedical epigenetics2014
Epigenetic Regulation of Infant Neurobehavioral Outcomes.
Article in Medical epigenetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Effect of Musical Stimulation on Placental Programming and Neurodevelopment Outcome of Preterm Infants: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Placental malaria induces a unique methylation profile associated with fetal growth restriction.Epigenetics · 2025Article
- Prenatal and perinatal factors associated with neonatal neurobehavioral profiles in the ECHO Program.Pediatric research · 2023Article
- The placenta epigenome-brain axis: placental epigenomic and transcriptomic responses that preprogram cognitive impairment.Epigenomics · 2022Article
- Heavy metals and metalloids exposure andFrontiers in reproductive health · 2022Review
- Differential Placental DNA Methylation ofFrontiers in pediatrics · 2022Article
- Relationships among Inorganic Arsenic, Nutritional Status CpG Methylation and microRNAs: A Review of the Literature.Epigenetics insights · 2021Review
- Environmental influences on placental programming and offspring outcomes following maternal immune activation.Brain, behavior, and immunity · 2020Article
- Maternal hair cortisol levels as a novel predictor of neonatal abstinence syndrome severity: A pilot feasibility study.Developmental psychobiology · 2020Article
- An Integrated Socio-Environmental Model of Health and Well-Being: a Conceptual Framework Exploring the Joint Contribution of Environmental and Social Exposures to Health and Disease Over the Life Span.Current environmental health reports · 2018Review
- Maternal Choline Supplementation during Normal Murine Pregnancy Alters the Placental Epigenome: Results of an Exploratory Study.Nutrients · 2018Article
- Placental CpG methylation of infants born extremely preterm predicts cognitive impairment later in life.PloS one · 2018Article
- Review
- Regions of variable DNA methylation in human placenta associated with newborn neurobehavior.Epigenetics · 2016Article
- Epigenome-Wide Assessment of DNA Methylation in the Placenta and Arsenic Exposure in the New Hampshire Birth Cohort Study (USA).Environmental health perspectives · 2016Article
- Distress During Pregnancy: Epigenetic Regulation of Placenta Glucocorticoid-Related Genes and Fetal Neurobehavior.The American journal of psychiatry · 2016Article
- DNA methylation changes in the placenta are associated with fetal manganese exposure.Reproductive toxicology (Elmsford, N.Y.) · 2015Article
- In utero arsenic exposure and epigenome-wide associations in placenta, umbilical artery, and human umbilical vein endothelial cells.Epigenetics · 2015Article
- The developmental basis of epigenetic regulation of HTR2A and psychiatric outcomes.Journal of cellular biochemistry · 2014Review
- Combined neurodevelopmental exposure to deltamethrin and corticosterone is associated with Nr3c1 hypermethylation in the midbrain of male mice.Neurotoxicology and teratologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
During fetal development and early-infancy, environmental signals can induce epigenetic changes that alter neurobehavioral development and later-life mental health. Several neurodevelopmental genetic diseases influence epigenetic regulatory genes and genomic imprinting. Recently, brain epigenetic marks have been involved in idiopathic neurodevelopmental disorders including autism spectrum disorders (ASD). The placenta is an important regulator of the intrauterine environment that links maternal and fetal nervous systems. Placental epigenetic signatures have been associated with neurodevelopment of healthy newborns quantified through the NICU Network Neurobehavioral Scales (NNNS). Associations have been observed for DNA methylation of genes involved in cortisol (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.