Evidence map›Paper›PMID 25088753›Full record

ArticleAnnals of epidemiology2014

The contribution of biogeographical ancestry and socioeconomic status to racial/ethnic disparities in type 2 diabetes mellitus: results from the Boston Area Community Health Survey.

Rebecca S Piccolo, Neil Pearce, Andre B Araujo, John B McKinlay

Abstract read
In one paragraph

Article in Annals of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Racial and Ethnic Disparities in Prevalence and Care of Patients With Type 2 Diabetes.Clinical diabetes : a publication of the American Diabetes Association · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rebecca S PiccoloDepartment of Epidemiology, New England Research Institutes, 480 Pleasant Street, Watertown, MA; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK. Electronic address: rpiccolo@neriscience.com.
Neil PearceDepartment of Medical Statistics, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK.
Andre B AraujoDepartment of Epidemiology, New England Research Institutes, 480 Pleasant Street, Watertown, MA.
John B McKinlayDepartment of Epidemiology, New England Research Institutes, 480 Pleasant Street, Watertown, MA.

Funding

Upstream Contributors to Downstream Disparities in Type 2 Diabetes - A Multi-LeveR01DK080786 · NIDDK · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, JOHN B · 2009 to 2013
$3.3M
Epidemiology of Precursors to Type 2 DiabetesK24DK080140 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MEIGS, JAMES B · 2007 to 2016
$1.9M
NIDDK NIH HHS DK080140NIDDK NIH HHS DK080786NIDDK NIH HHS K24 DK080140NIDDK NIH HHS R01 DK080786
6 · The paper itself

Abstract

purposeRacial/ethnic disparities in the incidence of type 2 diabetes mellitus (T2DM) are well documented, and many researchers have proposed that biogeographical ancestry (BGA) may play a role in these disparities. However, studies examining the role of BGA on T2DM have produced mixed results to date. Therefore, the objective of this research was to quantify the contribution of BGA to racial/ethnic disparities in T2DM incidence controlling for the mediating influences of socioeconomic factors.

methodsWe analyzed data from the Boston Area Community Health Survey, a prospective cohort with approximately equal numbers of black, Hispanic, and white participants. We used 63 ancestry-informative markers to calculate the percentages of participants with West African and Native American ancestry. We used logistic regression with G-computation to analyze the contribution of BGA and socioeconomic factors to racial/ethnic disparities in T2DM incidence.

resultsWe found that socioeconomic factors accounted for 44.7% of the total effect of T2DM attributed to black race and 54.9% of the effect attributed to Hispanic ethnicity. We found that BGA had almost no direct association with T2DM and was almost entirely mediated by self-identified race/ethnicity and socioeconomic factors.

conclusionsIt is likely that nongenetic factors, specifically socioeconomic factors, account for much of the reported racial/ethnic disparities in T2DM incidence.

Indexed as

Effect Modifier, EpidemiologicHealth Status DisparitiesSocial ClassAdultAgedAmerican Indian or Alaska NativeBlack or African AmericanBlack PeopleBostonCausalityComputers, MolecularDiabetes Mellitus, Type 2EthnicityFemaleGenetic Predisposition to DiseaseHealth SurveysBiogeographic ancestryCausal modelingMediationRacial/ethnic disparitiesSocioeconomic statusType 2 diabetes

Identifiers

PMID25088753
PMCPMC4145472

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.