ArticleJournal of psychiatric research2014
Proton magnetic resonance spectroscopy (MRS) in on-line game addiction.
Article in Journal of psychiatric research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Electro-acupuncture treatment for internet addiction: Evidence of normalization of impulse control disorder in adolescents.Chinese journal of integrative medicine · 2017Trial
- Higher striatal glutamate in male youth with internet gaming disorder.European archives of psychiatry and clinical neuroscience · 2024Article
- Proton magnetic resonance spectroscopy (MRS) in individuals with internet gaming.Frontiers in psychiatry · 2022Article
- Biochemical Correlates of Video Game Use: From Physiology to Pathology. A Narrative Review.Life (Basel, Switzerland) · 2021Review
- Autistic Traits and Attention-Deficit Hyperactivity Disorder Symptoms Predict the Severity of Internet Gaming Disorder in an Italian Adult Population.Brain sciences · 2021Article
- A Comparison of Risk and Protective Factors for Excessive Internet Game Play between Koreans in Korea and Immigrant Koreans in the United States.Journal of Korean medical science · 2019Article
- Personality and Psychological Factors of Problematic Internet Gamers Seeking Hospital Treatment.Frontiers in psychiatry · 2019Article
- Diagnostic and Classification Considerations Regarding Gaming Disorder: Neurocognitive and Neurobiological Features.Frontiers in psychiatry · 2019Article
- Treatment efficacy of a specialized psychotherapy program for Internet Gaming Disorder.Journal of behavioral addictions · 2018Article
- A cohort study of patients seeking Internet gaming disorder treatment.Journal of behavioral addictions · 2018Article
- Internet gaming disorder in adolescence: Psychological characteristics of a clinical sample.Journal of behavioral addictions · 2018Article
- The Treatment of Internet Gaming Disorder: a Brief Overview of the PIPATIC Program.International journal of mental health and addiction · 2018Article
- An Update Overview on Brain Imaging Studies of Internet Gaming Disorder.Frontiers in psychiatry · 2017Review
- White matter connectivity and Internet gaming disorder.Addiction biology · 2016Article
- Behavioral addictions in addiction medicine: from mechanisms to practical considerations.Progress in brain research · 2016Review
- Neuroscience of Internet Pornography Addiction: A Review and Update.Behavioral sciences (Basel, Switzerland) · 2015Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Recent brain imaging studies suggested that both the frontal and temporal cortices are important candidate areas for mediating the symptoms of internet addiction. We hypothesized that deficits of prefrontal and temporal cortical function in patients with on-line game addiction (PGA) would be reflected in decreased levels of N-acetyl aspartate (NAA) and cytosolic, choline containing compound (Cho). Seventy three young PGA and 38 age and sex matched healthy control subjects were recruited in the study. Structural MR and (1)H MRS data were acquired using a 3.0 T MRI scanner. Voxels were sequentially placed in right frontal cortex and right medial temporal cortices. In the right frontal cortex, the levels of NAA in PGA were lower than those in healthy controls. In the medial temporal cortex, the levels of Cho in PGA participants were lower than those observed in healthy controls. The Young Internet Addiction Scale (YIAS) scores and perseverative responses in PGA were negatively correlated with the level of NAA in right frontal cortex. The Beck Depressive Inventory (BDI) scores in the PGA cohort were negatively correlated with Cho levels in the right temporal lobe. To the best of our knowledge, this is the first MRS study of individuals with on-line game addiction. Although, the subjects with on-line game addiction in the current study were free from psychiatric co-morbidity, patients with on-line game addiction appear to share characteristics with ADHD and MDD in terms of neurochemical changes in frontal and temporal cortices.
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