Evidence map›Paper›PMID 25088238›Full record

ArticlePediatric obesity2015

Maternal obesity influences the relationship between location of neonate fat mass and total fat mass.

H R Hull, J Thornton, C Paley, K Navder, D Gallagher

Abstract read
In one paragraph

Article in Pediatric obesity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

H R HullDepartment of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City, KS, USA.
J ThorntonNew York Obesity Nutrition Research Center, Columbia University, St. Luke's-Roosevelt Hospital, New York, NY, USA.
C PaleyDepartment of Pediatrics, St. Luke's-Roosevelt Hospital, New York, NY, USA.
K NavderDepartment of Nutritional Sciences, Hunter College, New York, NY, USA.
D GallagherNew York Obesity Nutrition Research Center, Columbia University, St. Luke's-Roosevelt Hospital, New York, NY, USA.

Funding

RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
WEIGHT LOSS--BONE &SKELETAL MUSCLE HOMEOSTASIS IN NIDDMP01DK042618 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI GALLAGHER, DYMPNA · 1990 to 2005
$7.8M
Kansas BIRCWH Career Development Program Women's HealthK12HD052027 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI CARLSON, SUSAN E · 2005 to 2014
$5.0M
OBESITY RESEARCH CENTER TRAINING PROGRAMT32DK007559 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI DYMPNA GALLAGHER · 1989 to 2026
$4.3M
NCATS NIH HHS UL1-TR40040NICHD NIH HHS 5K12HD052027NICHD NIH HHS K12 HD052027NIDDK NIH HHS P01 DK042618NIDDK NIH HHS P30 DK026687NIDDK NIH HHS P30-DK-26687NIDDK NIH HHS R01DK042618NIDDK NIH HHS T32 DK007559NIDDK NIH HHS T32-DK07559
6 · The paper itself

Abstract

backgroundIt is suggested that maternal obesity perpetuates offspring obesity to future generations.

objectiveTo determine whether location of neonate fat mass (FM: central vs. peripheral) is related to total neonate FM and whether maternal obesity influences this relationship.

methodsNeonate body composition and skin-fold thicknesses were assessed in healthy neonates (n = 371; 1-3 days old). Linear regression models examined the relationship between total FM and location of FM (central vs. peripheral). Location of FM was calculated by skin-folds: peripheral was the sum of (biceps and triceps)/2 and central was represented by the subscapular skin-fold.

resultsA significant interaction was found for location of FM and maternal obesity. Holding all predictors constant, in offspring born to non-obese mothers, a 0.5 mm increase in central FM predicted a 15 g greater total FM, whereas a 0.5 mm increase in peripheral FM predicted a 66 g greater total FM. However, in offspring born to obese mothers, a 0.5 mm increase in central FM predicted a 56 g total FM, whereas a 0.5 mm increase in peripheral FM predicted a 14 g greater total FM.

conclusionsThe relationship between total FM and location of FM is influenced by maternal obesity.

Indexed as

Body Fat DistributionMothersAdultBody CompositionFemaleHumansInfant, NewbornMaleObesitySkinfold ThicknessFat patternmaternal obesityneonate body compositionneonate fat mass

Identifiers

PMID25088238
PMCPMC4317390

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.