ArticleChemical senses2014
Somatostatin and corticotrophin releasing hormone cell types are a major source of descending input from the forebrain to the parabrachial nucleus in mice.
Article in Chemical senses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Article
- Pain-related cortico-limbic plasticity and opioid signaling.Neuropharmacology · 2023Review
- Perturbation of amygdala/somatostatin-nucleus of the solitary tract projections reduces sensitivity to quinine in a brief-access test.Brain research · 2022Article
- At the heart of the interoception network: Influence of the parasubthalamic nucleus on autonomic functions and motivated behaviors.Neuropharmacology · 2022Review
- Target-specific projections of amygdala somatostatin-expressing neurons to the hypothalamus and brainstem.Chemical senses · 2022Article
- Effects of Growth Hormone Receptor Ablation in Corticotropin-Releasing Hormone Cells.International journal of molecular sciences · 2021Article
- The Insula Cortex Contacts Distinct Output Streams of the Central Amygdala.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Distinct Populations of Amygdala Somatostatin-Expressing Neurons Project to the Nucleus of the Solitary Tract and Parabrachial Nucleus.Chemical senses · 2020Article
- Elucidation of the anatomy of a satiety network: Focus on connectivity of the parabrachial nucleus in the adult rat.The Journal of comparative neurology · 2016Article
- Genetic cell targeting uncovers specific neuronal types and distinct subregions in the bed nucleus of the stria terminalis.The Journal of comparative neurology · 2016Article
- High-resolution and cell-type-specific photostimulation mapping shows weak excitatory vs. strong inhibitory inputs in the bed nucleus of the stria terminalis.Journal of neurophysiology · 2016Article
- Topographic organizations of taste-responsive neurons in the parabrachial nucleus of C57BL/6J mice: An electrophysiological mapping study.Neuroscience · 2016Article
- Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala.Neuropharmacology · 2015Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The pontine parabrachial nucleus (PBN) receives substantial descending input from higher order forebrain regions that exerts inhibitory and excitatory influences on taste-evoked responses. Somatostatin (Sst) and corticotrophin releasing hormone (Crh) reporter mice were used in conjunction with injection of the retrograde tracer CTb-488 into the caudal PBN to determine the extent to which Sst and Crh cell types contribute to the descending pathways originating in the lateral hypothalamus (LH), central nucleus of the amygdala (CeA), bed nucleus of the stria terminalis (BNST), and insular cortex (IC). Five to 7 days following injections, the animals were euthanized and tissue sections prepared for confocal microscopy. Crh cell types in each forebrain site except IC project to the PBN with the greatest percentage originating in the BNST. For Sst cell types, the largest percentage of double-labeled cells was found in the CeA followed by the BNST. Few retrogradely labeled cells in the LH coexpressed Sst, whereas no double-labeled cells were observed in IC. The present results suggest that Sst and Crh cell types are a substantial component of the descending pathways from the amygdala and/or BNST to the PBN and are positioned to exert neuromodulatory effects on central taste processing.
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