ArticleJournal of neuro-oncology2014
Incidence of intracranial germ cell tumors by race in the United States, 1992-2010.
Article in Journal of neuro-oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Racial and ethnic disparities among children with primary central nervous system tumors in the US.Journal of neuro-oncology · 2021Pooled it
- Overlapping genetic etiology of pediatric and adult germ cell tumors.Journal of the National Cancer Institute · 2026Article
- Incidence of primary central nervous system tumors across age groups and histological groups in Osaka, Japan, 2011-2020.Journal of neuro-oncology · 2026Article
- Disparities in Neuro-Oncology.Current neurology and neuroscience reports · 2023Review
- Clinical characteristics of malignant germ cell tumors in adolescents: A multicenter 10-year retrospective study in Beijing.Cancer innovation · 2023Article
- Intracranial Germinomas: Diagnosis, Pathogenesis, Clinical Presentation, and Management.Current oncology reports · 2023Review
- Intracranial Germinoma-Association between Delayed Diagnosis, Altered Clinical Manifestations, and Prognosis.Cancers · 2023Article
- An international study evaluating the epidemiology of intracranial germ cell tumors in the native versus immigrant Japanese populations: the need for an international registry.Journal of neuro-oncology · 2022Review
- Growth Hormone Deficiency in Childhood Intracranial Germ Cell Tumor Survivors.Journal of endocrinology and metabolism · 2022Article
- Multifocal primary intracranial yolk sac tumor in an adult patient: a case report and literature review.Translational cancer research · 2022Article
- Nomograms to predict the prognosis in malignant ovarian germ cell tumors: a large cohort study.BMC cancer · 2022Article
- A pragmatic diagnostic approach to primary intracranial germ cell tumors and their treatment outcomes.CNS oncology · 2021Article
- Molecular exploration of paediatric intracranial germinomas from multi-ethnic Singapore.BMC neurology · 2020Article
- Effect of early radiotherapy initiation and high-dose chemotherapy on the prognosis of pediatric atypical teratoid rhabdoid tumors in different age groups.Journal of neuro-oncology · 2020Article
- Treatment and survival of primary intracranial germ cell tumors: a population-based study using SEER database.Journal of cancer research and clinical oncology · 2020Article
- Histopathology of Parasellar Neoplasms.Neuroendocrinology · 2020Review
- Prenatal Exposure to Air Toxics and Malignant Germ Cell Tumors in Young Children.Journal of occupational and environmental medicine · 2019Article
- A Rare Localized Pituitary Stalk Germinoma Presenting in the Third Decade.Case reports in endocrinology · 2018Article
- Family history of cancer in children and adolescents with germ cell tumours: a report from the Children's Oncology Group.British journal of cancer · 2018Article
- Risk of malignant childhood germ cell tumors in relation to demographic, gestational, and perinatal characteristics.Cancer epidemiology · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Little is known about the etiology of intracranial germ cell tumors (iGCTs), although international incidence data suggest that the highest incidence rates occur in Asian countries. In this analysis, we used 1992-2010 data from the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) Program to determine whether rates of iGCT were also high in Asian/Pacific Islanders living in the United States. Frequencies, incidence rates and survival rates were evaluated for the entire cohort and for demographic subgroups based on sex, age category (0-9 and 10-29 years), race (white, black, and Asian/Pacific Islander), and tumor location (pineal gland vs. other) as sample size permitted. Analyses were conducted using SEER*Stat 8.1.2. We observed a significantly higher incidence rate of iGCT in Asian/Pacific Islanders compared with whites (RR = 2.05, 95 % CI 1.57-2.64, RR = 3.04, 95 % CI 1.75-5.12 for males and females, respectively) in the 10-29 year age group. This difference was observed for tumors located both in the pineal gland and for tumors in other locations. Five-year relative survival differed by demographic and tumor characteristics, although these differences were not observed in comparisons limited to cases treated with radiation. Increased incidence rates of iGCT in individuals of Asian descent in the SEER registry are in agreement with data from the International Agency for Research on Cancer, where Japan and Singapore were among the countries with highest incidence. The increased incidence in individuals of Asian ancestry in the United States suggests that underlying genetic susceptibility may play a role in the etiology of iGCT.
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