Evidence map›Paper›PMID 25086669›Full record

ArticleAIDS and behavior2015

Acceptability of HIV Pre-exposure Prophylaxis (PREP) Among People Who Inject Drugs (PWID) in a Canadian Setting.

Daniel J Escudero, Thomas Kerr, Evan Wood, Paul Nguyen, Mark N Lurie, Omar Sued, Brandon D L Marshall

Registry-linked trialAbstract read
In one paragraph

Article in AIDS and behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05977881 (Impact of a Novel HIV Peer Navigation and Overdose Prevention Intervention on Engagement in the HIV Prevention and Treatment Cascade), which is not on this map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05977881 nacompletednot on this mapstarted 2023, after this paper: background citation

Impact of a Novel HIV Peer Navigation and Overdose Prevention Intervention on Engagement in the HIV Prevention and Treatment Cascade

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2023 to 2026Enrolled493ConditionsHIV InfectionsArmsCHECKIT!
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Daniel J EscuderoDepartment of Epidemiology, School of Public Health, Brown University, 121 South Main Street, Box G-S-12-2, Providence, RI, USA.
Thomas Kerr
Evan Wood
Paul Nguyen
Mark N Lurie
Omar Sued
Brandon D L Marshall
Brown University · USSt. Paul's Hospital · CAFundación Huésped · ARUniversity of British Columbia · CA

Funding

SYRINGE ACCESS AND RISK FACTORS ON HIV TRANSMISSIONR01DA011591 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI KERR, THOMAS · 1998 to 2014
$5.9M
Impact of Antiretroviral Therapy on HIV Epidemic DynamicsR01MH083539 · NIMH · BROWN UNIVERSITY · PI LURIE, MARK NATHAN · 2009 to 2012
$2.2M
Partnerships for the Next Generation of HIV Social Science in South AfricaR24HD077976 · NICHD · BROWN UNIVERSITY · PI COLVIN, CHRISTOPHER JAMES, LURIE, MARK NATHAN · 2013 to 2017
$1.9M
Estimating the impact of acute-stage HIV transmission among drug usersF31DA037808 · NIDA · BROWN UNIVERSITY · PI ESCUDERO, DANIEL · 2014 to 2015
$86k
CIHRNICHD NIH HHS 1R24HD077976-01NICHD NIH HHS R24 HD077976NIDA NIH HHS F31 DA037808NIDA NIH HHS F31-DA037808NIDA NIH HHS R01 DA011591NIDA NIH HHS R01DA011591NIMH NIH HHS 1R01MH083539-01NIMH NIH HHS R01 MH083539
6 · The paper itself

Abstract

A recent clinical trial provided evidence that pre-exposure prophylaxis (PrEP) has the potential to prevent HIV infection among people who inject drugs (PWID). We examined willingness to use PrEP among HIV-negative PWID in Vancouver, Canada (n = 543) to inform PrEP implementation efforts. One third (35.4 %) expressed willingness to use PrEP, with adjusted models indicating that younger age, no regular employment, requiring help injecting, engaging in sex work, and reporting multiple recent sexual partners were positively associated with willingness to use PrEP. Although willingness to use PrEP was low, PrEP was acceptable to some PWID at heightened risk for HIV infection.

Indexed as

Pre-Exposure ProphylaxisSexual BehaviorAdultAnti-HIV AgentsCanadaFemaleHIV InfectionsHumansMaleMiddle AgedPatient Acceptance of Health CareProspective StudiesRisk-TakingSubstance Abuse, IntravenousAnti-HIV Agents

Identifiers

PMID25086669
PMCPMC4315758
OpenAlexW2462399489

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.