Evidence map›Paper›PMID 25086372›Full record

ReviewAdvanced drug delivery reviews2014

New radiotracers for imaging of vascular targets in angiogenesis-related diseases.

Hao Hong, Feng Chen, Yin Zhang, Weibo Cai

Abstract readReview
In one paragraph

Review in Advanced drug delivery reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. A Clinical Feasibility Study to Image Angiogenesis in Patients with Arteriovenous Malformations UsingJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Trial
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Roles of Non-coding RNAs and Angiogenesis in Glioblastoma.Frontiers in cell and developmental biology · 2021
    Review
  11. Review
  12. Antibody-Based Tracers for PET/SPECT Imaging of Chronic Inflammatory Diseases.Chembiochem : a European journal of chemical biology · 2019
    Review
  13. Review
  14. Targeting PSMA by radioligands in non-prostate disease-current status and future perspectives.European journal of nuclear medicine and molecular imaging · 2018
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hao HongDepartment of Radiology, University of Wisconsin - Madison, WI, USA. Electronic address: hhong@uwhealth.org.
Feng ChenDepartment of Radiology, University of Wisconsin - Madison, WI, USA.
Yin ZhangDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, MD, USA.
Weibo CaiDepartment of Radiology, University of Wisconsin - Madison, WI, USA; Department of Medical Physics, University of Wisconsin - Madison, WI, USA; University of Wisconsin Carbone Cancer Center, Madison, WI, USA. Electronic address: wcai@uwhealth.org.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
Novel Combination Therapy for Prostate CancerR01CA169365 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CAI, WEIBO · 2013 to 2015
$903k
NCI NIH HHS 1R01CA169365NCI NIH HHS P30 CA014520NCI NIH HHS P30CA014520NCI NIH HHS R01 CA169365
6 · The paper itself

Abstract

Tremendous advances over the last several decades in positron emission tomography (PET) and single photon emission computed tomography (SPECT) allow for targeted imaging of molecular and cellular events in the living systems. Angiogenesis, a multistep process regulated by the network of different angiogenic factors, has attracted world-wide interests, due to its pivotal role in the formation and progression of different diseases including cancer, cardiovascular diseases (CVD), and inflammation. In this review article, we will summarize the recent progress in PET or SPECT imaging of a wide variety of vascular targets in three major angiogenesis-related diseases: cancer, cardiovascular diseases, and inflammation. Faster drug development and patient stratification for a specific therapy will become possible with the facilitation of PET or SPECT imaging and it will be critical for the maximum benefit of patients.

Indexed as

Positron-Emission TomographyRadiopharmaceuticalsTomography, Emission-Computed, Single-PhotonAnimalsCardiovascular DiseasesHumansInflammationNeoplasmsNeovascularization, PathologicRadiopharmaceuticalsAngiogenesisCancerCardiovascular diseaseInflammationPositron emission tomography (PET)Single-photon emission computed tomography (SPECT)

Identifiers

PMID25086372
PMCPMC4169744

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.