Evidence map›Paper›PMID 25086176›Full record

ReviewJournal of immunology (Baltimore, Md. : 1950)2014

Dendritic cells and B cells: unexpected partners in Th2 development.

Beatriz León, André Ballesteros-Tato, Frances E Lund

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of immunology (Baltimore, Md. : 1950), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Anti-CD20 treatment attenuates Th2 cell responses: implications for the role of lung follicular mature B cells in the asthmatic mice.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Role of B cells in TThe Journal of allergy and clinical immunology · 2018
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Beatriz LeónDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294; and.
André Ballesteros-TatoDivision of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL 35294.
Frances E LundDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294; and flund@uab.edu.
University of Alabama at Birmingham · US

Funding

Controlling Th2 immunity by tuning CXCL13 dependent DC migration in lymph nodesR01AI104725 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LUND, FRANCES E. · 2013 to 2017
$1.8M
NIAID NIH HHS R01 AI104725
6 · The paper itself

Abstract

Although we have known for decades that B cells contribute to immune responses by secreting Ab, it is now clear that they are more than simply factories for Ig production, and they also play key roles as modulators of T cell-dependent immunity. Indeed, the evidence showing that Ag-presenting and cytokine-producing B cells can alter the magnitude and quality of CD4 T cell responses continues to grow. In this article, we review the data showing that B cells, working in partnership with dendritic cells, regulate the development of Th2 cells and the subsequent allergic response.

Indexed as

AnimalsB-LymphocytesCell DifferentiationDendritic CellsHistocompatibility Antigens Class IIHumansHypersensitivityLymphocyte ActivationMiceTh2 CellsHistocompatibility Antigens Class II

Identifiers

PMID25086176
PMCPMC4233146
OpenAlexW1655951263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.