Evidence map›Paper›PMID 25085959›Full record

ReviewCold Spring Harbor perspectives in medicine2014

Fungi on the skin: dermatophytes and Malassezia.

Theodore C White, Keisha Findley, Thomas L Dawson, Annika Scheynius, Teun Boekhout, Christina A Cuomo, Jun Xu, Charles W Saunders

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 1 synthesis or guideline pooled it, 237 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Article
  7. Update on the epidemiology of dermatophytosis in Isfahan, Iran over the past decade.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  8. Animals : an open access journal from MDPI · 2025
    Review
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  14. Review
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Theodore C WhiteSchool of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri 64110.
Keisha FindleySocial and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892.
Thomas L DawsonProcter & Gamble Company, Singapore 138547.
Annika ScheyniusDepartment of Medicine Solna, Translational Immunology Unit, Karolinska Institutet and University Hospital, Stockholm, Sweden SE-141 86.
Teun BoekhoutCBS-KNAW Fungal Biodiversity Centre, 3584 CT, Utrecht, The Netherlands.
Christina A CuomoBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142.
Jun XuProcter & Gamble Company, Mason, Ohio 45040.
Charles W SaundersProcter & Gamble Company, Mason, Ohio 45040.
Procter & Gamble (United States) · USBroad Institute · USKarolinska University Hospital · SENational Institutes of Health · USUniversity of Missouri–Kansas City · USWesterdijk Fungal Biodiversity Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several human skin diseases and disorders are associated with two groups of fungi, the dermatophytes and Malassezia. Although these skin-related problems are not generally life threatening, they are among the most common diseases and disorders of mankind. These fungi are phylogenetically divergent, with the dermatophytes within the Ascomycota and Malassezia within Basidiomycota. Genome analysis indicates that the adaptations to the skin environment are different in these two groups of fungi. Malassezia are dependent on host lipids and secrete lipases and phospholipases that likely release host fatty acids. The dermatophytes encode multiple enzymes with potential roles in modulating host interactions: polyketide synthases, nonribosomal peptide synthetases, LysM, proteases, kinases, and pseudokinases. These two fungal groups have maximized their interactions with the host using two very different mechanisms.

Indexed as

ArthrodermataceaeDandruffDermatitis, AtopicDermatitis, SeborrheicDermatomycosesGenome, FungalHost-Pathogen InteractionsHumansMalasseziaMicrobiotaPhylogenySkinTinea Versicolor

Identifiers

PMID25085959
PMCPMC4109575
OpenAlexW2149273506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.