Evidence map›Paper›PMID 25085954›Full record

ArticleGastroenterology report2014

Higher prevalence of colon polyps in patients with Barrett's esophagus: a case-control study.

Arthi Kumaravel, Prashanthi N Thota, Hyun-Ju Lee, Tushar Gohel, Mehulkumar K Kanadiya, Rocio Lopez, Madhusudhan R Sanaka

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastroenterology report, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Factors Associated with Colorectal Polyps in Middle-Aged and Elderly Populations.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Arthi KumaravelCenter of Excellence for Barrett's Esophagus, Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio, USA and Department of Biostatistics, Cleveland Clinic, Cleveland, Ohio, USA.
Prashanthi N ThotaCenter of Excellence for Barrett's Esophagus, Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio, USA and Department of Biostatistics, Cleveland Clinic, Cleveland, Ohio, USA thotap@ccf.org.
Hyun-Ju LeeCenter of Excellence for Barrett's Esophagus, Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio, USA and Department of Biostatistics, Cleveland Clinic, Cleveland, Ohio, USA.
Tushar GohelCenter of Excellence for Barrett's Esophagus, Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio, USA and Department of Biostatistics, Cleveland Clinic, Cleveland, Ohio, USA.
Mehulkumar K KanadiyaCenter of Excellence for Barrett's Esophagus, Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio, USA and Department of Biostatistics, Cleveland Clinic, Cleveland, Ohio, USA.
Rocio LopezCenter of Excellence for Barrett's Esophagus, Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio, USA and Department of Biostatistics, Cleveland Clinic, Cleveland, Ohio, USA.
Madhusudhan R SanakaCenter of Excellence for Barrett's Esophagus, Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio, USA and Department of Biostatistics, Cleveland Clinic, Cleveland, Ohio, USA.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsBarrett's esophagus (BE) and colorectal neoplasms share similar risk factors. Previous studies have shown variable prevalence of colon polyps in patients with BE. Our aims were to determine the prevalence and incidence of colon polyps in patients with BE, compared to those without BE.

methodsIn this case-control study, the study group included patients, aged 50-75 years, with biopsy-proven BE, who underwent colonoscopy at Cleveland Clinic from January 2002 to December 2011. The control group consisted of age- and sex-matched patients who underwent colonoscopy and also an endoscopy with no evidence of BE during the same time period. Exclusion criteria for both groups were family- or personal previous history of colon cancer or polyps, prior colonic resection, inflammatory bowel disease and familial polyposis syndromes. Patient demographics, comorbidities, medication use and endoscopic and colonoscopic details were collected, including biopsy results.

resultsA total of 519 patients were included in the study; 173 patients with BE in the study group and 346 without BE in the control group. Mean age at index colonoscopy was 61 ± 8 years and 75% of patients were male. On index colonoscopy, patients with BE were more likely to have polyps than controls (45% vs 32%, respectively; P = 0.003). Patients underwent between one and five colonoscopies during the follow-up. On multivariate analysis-after adjusting for age, gender and diabetes-patients with BE were 80% more likely to have any type of polyp, and 50% more likely to have adenomas found during colonoscopy.

conclusionsPatients with BE had higher prevalence and incidence of colon polyps. This has important clinical implications for screening and surveillance in BE patients.

Indexed as

Barrett’s esophaguscancer preventioncolon polyps

Identifiers

PMID25085954
PMCPMC4219145
OpenAlexW2159503031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.