Evidence map›Paper›PMID 25085225›Full record

Trial reportDrug and alcohol dependence2014

Randomized, controlled pilot trial of a smartphone app for smoking cessation using acceptance and commitment therapy.

Jonathan B Bricker, Kristin E Mull, Julie A Kientz, Roger Vilardaga, Laina D Mercer, Katrina J Akioka, Jaimee L Heffner

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 202 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
202citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06552494 nacompletednot on this mapstarted 2020, after this paper: background citation

Developing and Testing an Integrated mHealth Learning Program for Gynecological Cancer

TypeinterventionalSponsorChang Gung Memorial HospitalRan2020 to 2024Enrolled67ConditionsMobile HealthArmsL-mHealth program
NCT07516314 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant (HCT) Patients (ACTivate)

TypeinterventionalSponsorAnthony Sung, MDRan2026 to 2031Enrolled476ConditionsStem Cell Transplant PatientsArmsACTivate sessions
3 · Its place in the literature

Who cites it

202 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Economic Evaluation of Pharmacist-Led Digital Health Interventions: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Mindfulness for smoking cessation.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Smoking Cessation Apps: A Systematic Review of Format, Outcomes, and Features.International journal of environmental research and public health · 2021
    Pooled it
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  9. Mobile phone-based interventions for smoking cessation.The Cochrane database of systematic reviews · 2016
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  16. Behavioral Activation mHealth Application for Smoking Cessation: A Randomized Controlled Pilot Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
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  19. Digital Smoking Cessation With a Comprehensive Guideline-Based App-Results of a Nationwide, Multicentric, Parallel, Randomized Controlled Trial in Germany.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
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142 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonathan B BrickerFred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue N., Seattle, WA 98109, USA; University of Washington, Department of Psychology, Box 351525, Seattle, WA 98195, USA. Electronic address: jbricker@fhcrc.org.
Kristin E MullFred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue N., Seattle, WA 98109, USA.
Julie A KientzUniversity of Washington, Department of Human Centered Design and Engineering, Box 352315, Seattle, WA 98195, USA.
Roger VilardagaFred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue N., Seattle, WA 98109, USA; University of Washington, Department of Psychiatry and Behavioral Sciences, Box 356560, Seattle, WA 98195, USA.
Laina D MercerFred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue N., Seattle, WA 98109, USA.
Katrina J AkiokaFred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue N., Seattle, WA 98109, USA.
Jaimee L HeffnerFred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue N., Seattle, WA 98109, USA.

Funding

Randomized Trial of Web-Delivered Acceptance Therapy for Smoking CessationR01CA166646 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BRICKER, JONATHAN B · 2013 to 2017
$3.4M
Acceptance & Commitment Therapy for Smoking CessationR01CA151251 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BRICKER, JONATHAN B · 2010 to 2014
$3.0M
Improving Mental Health Care in Safety Net Medical SettingsT32MH082709 · NIMH · UNIVERSITY OF WASHINGTON · PI COMTOIS, KATHERINE ANNE · 2010 to 2014
$1.4M
Targeted Intervention for Bipolar SmokersK23DA026517 · NIDA · UNIVERSITY OF CINCINNATI · PI HEFFNER, JAIMEE · 2009 to 2013
$654k
Innovative Smartphone Application for Quitting Smoking among Seriously Mentally IK99DA037276 · NIDA · UNIVERSITY OF WASHINGTON · PI VILARDAGA, ROGER · 2014 to 2015
$344k
NCI NIH HHS R01 CA151251NCI NIH HHS R01CA151251NCI NIH HHS R01 CA166646NCI NIH HHS R01CA166646NIDA NIH HHS K23 DA026517NIDA NIH HHS K23DA026517NIDA NIH HHS K99 DA037276NIMH NIH HHS T32 MH082709NIMH NIH HHS T32MH082709
6 · The paper itself

Abstract

backgroundThere is a dual need for (1) innovative theory-based smartphone applications for smoking cessation and (2) controlled trials to evaluate their efficacy. Accordingly, this study tested the feasibility, acceptability, preliminary efficacy, and mechanism of behavioral change of an innovative smartphone-delivered acceptance and commitment therapy (ACT) application for smoking cessation vs. an application following US Clinical Practice Guidelines.

methodAdult participants were recruited nationally into the double-blind randomized controlled pilot trial (n=196) that compared smartphone-delivered ACT for smoking cessation application (SmartQuit) with the National Cancer Institute's application for smoking cessation (QuitGuide).

resultsWe recruited 196 participants in two months. SmartQuit participants opened their application an average of 37.2 times, as compared to 15.2 times for QuitGuide participants (p<0001). The overall quit rates were 13% in SmartQuit vs. 8% in QuitGuide (OR=2.7; 95% CI=0.8-10.3). Consistent with ACT's theory of change, among those scoring low (below the median) on acceptance of cravings at baseline (n=88), the quit rates were 15% in SmartQuit vs. 8% in QuitGuide (OR=2.9; 95% CI=0.6-20.7).

conclusionsACT is feasible to deliver by smartphone application and shows higher engagement and promising quit rates compared to an application that follows US Clinical Practice Guidelines. As results were limited by the pilot design (e.g., small sample), a full-scale efficacy trial is now needed.

Indexed as

Cell PhoneMobile ApplicationsAcceptance and Commitment TherapyAdultBehavior, AddictiveDouble-Blind MethodFemaleHumansMalePilot ProjectsSmoking CessationTherapy, Computer-AssistedTreatment OutcomeAcceptancemHealthMindfulnessNicotine dependenceSmoking cessationTelephone

Identifiers

PMID25085225
PMCPMC4201179

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.