ReviewEukaryotic cell2014
Lager yeast comes of age.
Review in Eukaryotic cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed.
- Isolation and characterization of haploid heterothallic beer yeasts.Applied microbiology and biotechnology · 2025Article
- Mosaic Genome of a British Cider Yeast.International journal of molecular sciences · 2023Article
- Co-Fermentations of Kveik with Non-Conventional Yeasts for Targeted Aroma Modulation.Microorganisms · 2022Article
- Polygenic Analysis of Tolerance to Carbon Dioxide Inhibition of Isoamyl Acetate "Banana" Flavor Production in Yeast RevealsApplied and environmental microbiology · 2022Article
- Aneuploidy influences the gene expression profiles in Saccharomyces pastorianus group I and II strains during fermentation.PLoS genetics · 2022Article
- Genomic diversity, chromosomal rearrangements, and interspecies hybridization in the Ogataea polymorpha species complex.G3 (Bethesda, Md.) · 2021Article
- Article
- Overexpression ofMicroorganisms · 2019Article
- Ploidy Variation inFrontiers in genetics · 2018Article
- New Lager Brewery Strains Obtained by Crossing Techniques UsingApplied and environmental microbiology · 2017Article
- Industrial Relevance of Chromosomal Copy Number Variation in Saccharomyces Yeasts.Applied and environmental microbiology · 2017Review
- Fungi as a Source of Food.Microbiology spectrum · 2017Review
- Evolutionary restoration of fertility in an interspecies hybrid yeast, by whole-genome duplication after a failed mating-type switch.PLoS biology · 2017Article
- Novel brewing yeast hybrids: creation and application.Applied microbiology and biotechnology · 2017Review
- Copy number variations of genes involved in stress responses reflect the redox state and DNA damage in brewing yeasts.Cell stress & chaperones · 2016Article
- Complex Ancestries of Lager-Brewing Hybrids Were Shaped by Standing Variation in the Wild Yeast Saccharomyces eubayanus.PLoS genetics · 2016Article
- The genomics of microbial domestication in the fermented food environment.Current opinion in genetics & development · 2015Review
- The Genome Sequence of Saccharomyces eubayanus and the Domestication of Lager-Brewing Yeasts.Molecular biology and evolution · 2015Article
- The Genomic Aftermath of Hybridization in the Opportunistic Pathogen Candida metapsilosis.PLoS genetics · 2015Article
- Chromosomal Copy Number Variation in Saccharomyces pastorianus Is Evidence for Extensive Genome Dynamics in Industrial Lager Brewing Strains.Applied and environmental microbiology · 2015Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alcoholic fermentations have accompanied human civilizations throughout our history. Lager yeasts have a several-century-long tradition of providing fresh beer with clean taste. The yeast strains used for lager beer fermentation have long been recognized as hybrids between two Saccharomyces species. We summarize the initial findings on this hybrid nature, the genomics/transcriptomics of lager yeasts, and established targets of strain improvements. Next-generation sequencing has provided fast access to yeast genomes. Its use in population genomics has uncovered many more hybridization events within Saccharomyces species, so that lager yeast hybrids are no longer the exception from the rule. These findings have led us to propose network evolution within Saccharomyces species. This "web of life" recognizes the ability of closely related species to exchange DNA and thus drain from a combined gene pool rather than be limited to a gene pool restricted by speciation. Within the domesticated lager yeasts, two groups, the Saaz and Frohberg groups, can be distinguished based on fermentation characteristics. Recent evidence suggests that these groups share an evolutionary history. We thus propose to refer to the Saaz group as Saccharomyces carlsbergensis and to the Frohberg group as Saccharomyces pastorianus based on their distinct genomes. New insight into the hybrid nature of lager yeast will provide novel directions for future strain improvement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.