ArticleJournal of cardiac failure2014
Brief report: antisynthetase syndrome-associated myocarditis.
Article in Journal of cardiac failure, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- [Cardiac involvement in idiopathic inflammatory myopathies].Zeitschrift fur Rheumatologie · 2026Review
- Myocardial involvement in inflammatory myopathies: from subclinical disease to life-threatening myocarditis.Expert review of clinical immunology · 2026Review
- Article
- Cardiac Involvement in Idiopathic Inflammatory Myopathies.Journal of inflammation research · 2025Review
- Myocarditis in anti-synthetase syndrome: clinical features and diagnostic modalities.Rheumatology (Oxford, England) · 2024Article
- Myocarditis in Patients With Idiopathic Inflammatory Myopathies: Clinical Presentation and Outcomes.The Journal of rheumatology · 2023Article
- [Clinical and immunological characteristics of patients with anti-synthetase syndrome complicated with cardiac involvement].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2021Article
- Rare presentation of antisynthetase syndrome complicated by myocarditis resulting in sustained ventricular tachycardia.BMJ case reports · 2021Article
- Antisynthetase syndrome: A distinct disease spectrum.Journal of scleroderma and related disorders · 2020Review
- Management of Myocarditis in Myositis: Diagnosis and Treatment.Current rheumatology reports · 2020Review
- Case Report: Immune Mediated Necrotizing Myopathy With IgG Antibodies to 3-Hydroxy-3-Methylglutaryl-Coenzyme a Reductase (HMGCR) May Present With Acute Systolic Heart Failure.Frontiers in neurology · 2020Article
- A misdiagnosed case of antisynthetase syndrome complicated by myocarditis: when the cardiologist deals with rheumatology.Clinical rheumatology · 2019Review
- When your immune system falls out with your heart: an important lesson on antisynthetase myocarditis.BMJ case reports · 2018Article
- Review
- Myocarditis in Patients With Antisynthetase Syndrome: Prevalence, Presentation, and Outcomes.Medicine · 2015Observational
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe antisynthetase (AS) syndrome is characterized by autoimmune myopathy, interstitial lung disease, cutaneous involvement, arthritis, fever, and antibody specificity. We describe 2 patients with AS syndrome who also developed myocarditis, depressed biventricular function, and congestive heart failure. METHODS AND
resultsBoth patients were diagnosed with AS syndrome based on clinical manifestations, detection of serum AS antibodies, and myositis confirmation with the use of skeletal muscle magnetic resonance imaging and skeletal muscle biopsy. In addition, myocarditis resulting in heart failure was confirmed with the use of cardiac magnetic resonance imaging and from endomyocardial biopsy findings. After treatment for presumed AS syndrome-associated myocarditis, one patient recovered and the other patient died.
conclusionsAS syndrome is a rare entity with morbidity and mortality typically attributed to myositis and lung involvement. This is the first report of AS syndrome-associated myocarditis leading to congestive heart failure in 2 patients. Given the potentially fatal consequences, myocarditis should be considered in patients with AS syndrome presenting with heart failure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.