ArticlePloS one2014
Increased insomnia symptoms predict the onset of back pain among employed adults.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 5 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Associations between lifestyle-related risk factors and back pain: a systematic review and meta-analysis of Mendelian randomization studies.BMC musculoskeletal disorders · 2024Pooled it
- Pooled it
- Effectiveness of non-pharmacological interventions on sleep characteristics among adults with musculoskeletal pain and a comorbid sleep problem: a systematic review.Chiropractic & manual therapies · 2021Pooled it
- Sleep disturbances and back pain : Systematic review and meta-analysis.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2020Pooled it
- Effects of sleep changes on pain-related health outcomes in the general population: A systematic review of longitudinal studies with exploratory meta-analysis.Sleep medicine reviews · 2018Pooled it
- Low Back Pain and Psychosocial Work Factors Associated with Sleep Problems among University and Hospital Employees: A Cross-sectional Study.JMA journal · 2026Article
- Prevalence of Musculoskeletal Disorders in Dental Students and Dentists, and Its Relationship With Extra-Occupational Factors.European journal of dental education : official journal of the Association for Dental Education in Europe · 2026Article
- Article
- Relationship Between Sleep Disturbances and Chronic Pain: A Narrative Review.Clinics and practice · 2024Review
- Modifiable risk factors that mediate the effect of insomnia on the risk of low back pain: a network mendelian randomization study.Hereditas · 2024Article
- The Role of Anxiety and Depression in Shaping the Sleep-Pain Connection in Patients with Nonspecific Chronic Spinal Pain and Comorbid Insomnia: A Cross-Sectional Analysis.Journal of clinical medicine · 2024Article
- Sleep disturbance is associated with neck pain: a 3-year longitudinal study after the Great East Japan Earthquake.BMC musculoskeletal disorders · 2022Article
- Association of insomnia and daytime sleepiness with low back pain: A bidirectional mendelian randomization analysis.Frontiers in genetics · 2022Article
- Are Morphometric and Biomechanical Characteristics of Lumbar Multifidus Related to Pain Intensity or Disability in People With Chronic Low Back Pain After Considering Psychological Factors or Insomnia?Frontiers in psychiatry · 2022Article
- Sleep disturbance and pain in U.S. adults over 50: evidence for reciprocal, longitudinal effects.Sleep medicine · 2021Observational
- The Association between Sleep and Chronic Spinal Pain: A Systematic Review from the Last Decade.Journal of clinical medicine · 2021Review
- Move to health-a holistic approach to the management of chronic low back pain: an intervention and implementation protocol developed for a pragmatic clinical trial.Journal of translational medicine · 2021Article
- The effect of long-term poor sleep quality on risk of back-related disability and the modifying role of physical activity.Scientific reports · 2021Article
- Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study.Nature and science of sleep · 2020Article
- Multimodal Care in the Management of a Patient With Chronic Tendinopathy of the Biceps Femoris: A Case Report.Journal of chiropractic medicine · 2017Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBack pain is among the most prevalent pain disorders causing chronic disability among adults, and insomnia is a common co-morbidity. However, whether insomnia precedes back pain or vice versa remains unclear. The current study tested the temporal association between insomnia and back pain.
methodsA longitudinal design was used to investigate whether changes in insomnia over time predict the onset of back pain and vice versa. The study was conducted on a cohort of active healthy working adults (N = 2,131, 34% women) at three time points (T1, T2, and T3) over a period of 3.7 years (range = 2.2-5.12) years. Logistic regression analysis was used to test whether increased insomnia symptoms from T1 to T2 predicted the onset of new back pain. Ordinary least squares regression was used to test whether the existence of back pain at T2 predicted an increase in insomnia from T2 to T3.
resultsThe results indicated that after controlling for socioeconomic variables, self-reported health, lifestyle behaviors, and anthropometrics, a T1-T2 increase in insomnia symptoms was associated with a 1.40-fold increased risk of back pain at T3 (OR = 1.40; 95% CI = 1.10-1.71). No support was found for reverse causation; i.e., that back pain predicts subsequent increase in insomnia.
conclusionsInsomnia appears to be a risk factor in the development of back pain in healthy individuals. However, no evidence of reverse causation was found.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.