ArticleThe American journal of drug and alcohol abuse2014
Optimal neurocognitive, personality and behavioral measures for assessing impulsivity in cocaine dependence.
Article in The American journal of drug and alcohol abuse, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Impulsivity as a Risk Factor for Suicide in Bipolar Disorder.Frontiers in psychiatry · 2021Article
- Striatal functional connectivity in chronic ketamine users: a pilot study.The American journal of drug and alcohol abuse · 2020Article
- Decision-making processes as predictors of relapse and subsequent use in stimulant-dependent patients.The American journal of drug and alcohol abuse · 2016Article
- Marijuana Use Is Associated with Behavioral Approach and Depressive Symptoms in Adolescents and Emerging Adults.PloS one · 2016Article
- Brain perfusion in polysubstance users: relationship to substance and tobacco use, cognition, and self-regulation.Drug and alcohol dependence · 2015Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundImpulsivity may underlie the poor treatment retention and high relapse rates observed in cocaine-dependent persons. However, observed differences in measures of impulsivity between cocaine-dependent and healthy control participants often do not reach clinical significance, suggesting that the clinical relevance of these differences may be limited.
objectivesTo examine which measures of impulsivity (i.e. self-report impulsivity, self-report personality, neurocognitive testing) best distinguish cocaine-dependent and healthy control participants (i.e. showing differences at least 1.5 standard deviations [SD] from controls). Optimal measures were considered to demonstrate sufficient classification accuracy.
methodsSixty-five recently abstinent cocaine-dependent and 25 healthy control participants were assessed using select neurocognitive tests and self-report questionnaires including the NEO Personality Inventory-Revised (NEO-PI-R), Temperament and Character Inventory (TCI), Barratt Impulsiveness Scale (BIS-11a), and the Frontal Systems Behavior Scale (FrSBe).
resultsWhen corrected for years of education and gender, neurocognitive measures did not demonstrate clinically significant differences between cocaine-dependent and control participants. The personality measures TCI Purposefulness and Congruent Second Nature and NEO-PI-R Impulsiveness, and the self-rating measures FrSBe Disinhibition and BIS-11 Motor Impulsivity and Total successfully identified clinically meaningful elevations in impulsivity within cocaine-dependent participants (>1.5 SDs from controls). Furthermore, these measures achieved 84-93% accuracy in discriminating cocaine-dependent from control participants.
conclusionClinically significant neurocognitive impairment in cocaine-dependent participants was not observed in this sample. As the BIS-11 or FrSBe are brief to administer, accurate, and have been shown to predict treatment retention and relapse, these measures appear to be optimal, relative to the personality measures, for examining trait impulsivity in cocaine dependence.
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