Evidence map›Paper›PMID 25083802›Full record

Trial reportContemporary clinical trials2014

SMI life goals: description of a randomized trial of a collaborative care model to improve outcomes for persons with serious mental illness.

Amy M Kilbourne, Margretta Bramlet, Michelle M Barbaresso, Kristina M Nord, David E Goodrich, Zongshan Lai, Edward P Post, Daniel Almirall, Lilia Verchinina, Sonia A Duffy and 1 more

2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01244854 nacompletednot on this map

Life Goals Behavioral Change to Improve Outcomes for Veterans With SMI

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2010 to 2015Enrolled55ConditionsBipolar Disorder, Schizophrenia, Major Depressive Disorder, Chronic Affective DisordersArmsLife Goals Collaborative Care
NCT01487668 nacompletednot on this map

Life Goals Collaborative Care to Improve Health Outcomes in Mental Disorders

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2011 to 2015Enrolled304ConditionsBipolar Disorder, Schizophrenia, Major Depressive Disorder, Schizoaffective DisorderArmsLife Goals Collaborative Care
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Collaborative care approaches for people with severe mental illness.The Cochrane database of systematic reviews · 2024
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  12. Maternal schizophrenia and adverse birth outcomes: what mediates the risk?Social psychiatry and psychiatric epidemiology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Amy M KilbourneVA Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Mailstop 152, Ann Arbor, MI 48105, USA; Department of Psychiatry, University of Michigan Medical School, North Campus Research Complex, 2800 Plymouth Road, Building 16, Ann Arbor, MI 48109-2800, USA. Electronic address: Amy.Kilbourne@va.gov.
Margretta BramletVA Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Mailstop 152, Ann Arbor, MI 48105, USA. Electronic address: Margretta.bramlet@va.gov.
Michelle M BarbaressoVA Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Mailstop 152, Ann Arbor, MI 48105, USA. Electronic address: Michelle.barbaresso@va.gov.
Kristina M NordVA Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Mailstop 152, Ann Arbor, MI 48105, USA; Department of Psychiatry, University of Michigan Medical School, North Campus Research Complex, 2800 Plymouth Road, Building 16, Ann Arbor, MI 48109-2800, USA. Electronic address: kmnord@umich.edu.
David E GoodrichVA Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Mailstop 152, Ann Arbor, MI 48105, USA; Department of Psychiatry, University of Michigan Medical School, North Campus Research Complex, 2800 Plymouth Road, Building 16, Ann Arbor, MI 48109-2800, USA. Electronic address: David.Goodrich2@va.gov.
Zongshan LaiVA Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Mailstop 152, Ann Arbor, MI 48105, USA; Department of Psychiatry, University of Michigan Medical School, North Campus Research Complex, 2800 Plymouth Road, Building 16, Ann Arbor, MI 48109-2800, USA. Electronic address: Zongshan.Lai@va.gov.
Edward P PostVA Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Mailstop 152, Ann Arbor, MI 48105, USA; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: Edward.Post@va.gov.
Daniel AlmirallInstitute for Social Research, University of Michigan, 426 Thompson Street, Ann Arbor, MI 48104-2321, USA. Electronic address: dalmiral@umich.edu.
Lilia VerchininaVA Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Mailstop 152, Ann Arbor, MI 48105, USA. Electronic address: Lilia.verchinina@va.gov.
Sonia A DuffyVA Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Mailstop 152, Ann Arbor, MI 48105, USA; University of Michigan School of Nursing, Division of Health Promotion and Risk Reduction, 400 N Ingalls Bldg, Rm 3178, Ann Arbor, MI 48109-5482, USA. Electronic address: bump@umich.edu.
Mark S BauerCenter for Healthcare Organization and Implementation Research, VA Boston Healthcare System 152M, 150 South Huntington Avenue, Boston, MA 02130, USA; Department of Psychiatry, Harvard Medical School, 2 West, Room 305, 401 Park Drive, Boston, MA 02215, USA. Electronic address: Mark.Bauer@va.gov.
VA Ann Arbor Healthcare System · USVA Center for Clinical Management Research · USUniversity of Michigan–Ann Arbor · USHarvard University · US

Funding

THE REFINEMENT &APPLICATION OF MEDICAL DECISION MAKING IN PREVENTION SCIENCESP50DA010075 · NIDA · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI LANZA, STEPHANIE T · 1996 to 2014
$24.5M
Implementing Chronic Care Management for Bipolar DisorderR01MH079994 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KILBOURNE, AMY M · 2008 to 2012
$3.3M
NIDA NIH HHS P50 DA010075NIMH NIH HHS R01 MH079994
6 · The paper itself

Abstract

backgroundPersons with serious mental illnesses (SMI) are more likely to die earlier than the general population, primarily due to increased medical burden, particularly from cardiovascular disease (CVD). Life Goals Collaborative Care (LG-CC) is designed to improve health outcomes in SMI through self-management, care management, and provider support. This single-blind randomized controlled effectiveness study will determine whether patients with SMI receiving LG-CC compared to usual care (UC) experience improved physical health in 12 months.

methodsPatients diagnosed with SMI and at least one CVD risk factor receiving care at a VA mental health clinic were randomized to LG-CC or UC. LG-CC included five self-management sessions covering mental health symptom management reinforced through health behavior change, care coordination and health monitoring via a registry, and provider feedback. The primary outcome is change in physical health-related quality of life score (VR-12) from baseline to 12 months. Secondary outcomes include changes in mental health-related quality of life, CVD risk factors (blood pressure, BMI), and physical activity from baseline to 12 months later.

resultsOut of 304 enrolled, 139 were randomized to LG-CC and 145 to UC. Among patients completing baseline assessments (N = 284); the mean age was 55.2 (SD = 10.9; range 28-75 years), 15.6% were women, the majority (62%) were diagnosed with depression, and the majority (63%) were diagnosed with hypertension or were overweight (BMI mean ± SD = 33.3 ± 6.3). Baseline VR-12 physical health component score was below population norms (50.0 ± SD = 10) at 33.4 ± 11.0.

conclusionsFindings from this trial may inform initiatives to improve physical health for SMI patient populations.

Indexed as

GoalsAdultAgedBlood PressureBody Mass IndexCardiovascular DiseasesCooperative BehaviorExerciseFemaleHumansMaleMental DisordersMiddle AgedOverweightPatient-Centered CareProspective StudiesCare managementMood disordersSchizophreniaSelf-management

Identifiers

PMID25083802
PMCPMC4260928
OpenAlexW2103039072

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.