Evidence map›Paper›PMID 25083375›Full record

ArticleJournal of neurological surgery reports2014

Atypical presentation of sinonasal cellular schwannoma: a nonsolitary mass with osseous, orbital, and intracranial invasion.

John Gencarelli, Ryan Rourke, Tracey Ross, Denis H Gravel, Bibianna Purgina, David Jordan, Charles Agbi, Shaun J Kilty

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of neurological surgery reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Rare Schwannomas of Head and Neck and Review of Literature.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  2. Schwannoma of the sinonasal tract: case report with review of the literature.Annals of the Royal College of Surgeons of England · 2021
    Review
  3. Article
  4. Article
  5. Encapsulated Sinonasal Schwannoma Mimicking an Antrochoanal Polyp.Nigerian medical journal : journal of the Nigeria Medical Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

John GencarelliDepartment of Otolaryngology - Head and Neck Surgery, University of Ottawa, Ottawa, Ontario, Canada.
Ryan RourkeDepartment of Otolaryngology - Head and Neck Surgery, University of Ottawa, Ottawa, Ontario, Canada ; The Ottawa Hospital, Ottawa, Ontario, Canada.
Tracey RossDepartment of Otolaryngology - Head and Neck Surgery, University of Ottawa, Ottawa, Ontario, Canada ; The Ottawa Hospital, Ottawa, Ontario, Canada.
Denis H GravelThe Ottawa Hospital, Ottawa, Ontario, Canada ; Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Bibianna PurginaThe Ottawa Hospital, Ottawa, Ontario, Canada ; Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Ontario, Canada.
David JordanThe Ottawa Hospital, Ottawa, Ontario, Canada ; Department of Ophthalmology, University of Ottawa, Ottawa, Ontario, Canada.
Charles AgbiThe Ottawa Hospital, Ottawa, Ontario, Canada ; Division of Neurosurgery, University of Ottawa, Ottawa, Ontario, Canada.
Shaun J KiltyDepartment of Otolaryngology - Head and Neck Surgery, University of Ottawa, Ottawa, Ontario, Canada ; The Ottawa Hospital, Ottawa, Ontario, Canada ; The Ottawa Hospital Research Institute (OHRI), Ottawa, Ontario, Canada.
University of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Sinonasal cellular schwannoma represents < 4% of head and neck schwannomas. These benign tumors are typically confined to the nasal cavity or ethmoid sinus. We describe an atypical case of sinonasal cellular schwannoma with diffuse paranasal sinus involvement and both intraorbital and intracranial extension. Results A 62-year-old woman presented with a 6-month history of right orbital proptosis and right-sided headache. Subsequent imaging revealed an invasive paranasal sinus mass extending through the skull base and displacing the right orbit. Preoperative biopsies were not diagnostic but revealed a spindle cell lesion suspicious for malignancy based on lack of encapsulation, infiltration of the sinonasal submucosa, and osseous invasion. The patient underwent open skull base surgery, and pathology confirmed a S100-positive nonencapsulated cellular schwannoma. Conclusion An atypical case of sinonasal cellular schwannoma with intracranial extension is reported. Its presentation is contrary to the common view that these are isolated solitary lesions of the nasoethmoid region. We suggest that sinonasal cellular schwannoma be considered in the differential diagnosis of a poorly defined invasive paranasal sinus mass, particularly following biopsy.

Indexed as

cellular schwannomaintracranialnasal cavityparanasalsinuses

Identifiers

PMID25083375
PMCPMC4110123
OpenAlexW2018331090

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.