ReviewTherapeutic advances in drug safety2012
Impact of prescribed medications on patient safety in older people.
Review in Therapeutic advances in drug safety, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03501108 (Medication Rationalization for Older People Awaiting Long-term Nursing Home Care), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Medication Rationalization for Older People Awaiting Long-term Nursing Home Care: a Randomized Controlled Trial Using the STOPPfrail Criteria
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Attitudes Towards Deprescribing Among Older Adults with Limited Life Expectancy and Their Relatives: A Systematic Review.Drugs & aging · 2020Pooled it
- Antihypertensive withdrawal for the prevention of cognitive decline.The Cochrane database of systematic reviews · 2016Pooled it
- Trust first, concerns second: An international vignette study of older adults' preferences towards deprescribing statins.British journal of clinical pharmacology · 2026Article
- Development of a High-Risk Medication List for Australian Residential Aged Care: A Modified Delphi Study.Australasian journal on ageing · 2026Article
- Considerations in the Diagnosis and Management of Bronchiectasis in Older Adults.Clinics in geriatric medicine · 2025Review
- Associations of high-risk drug patterns with mortality among community-dwelling older adults: A 23-year prospective cohort study.PloS one · 2025Article
- Article
- Deprescribing Anticholinergics to Preserve Brain Health: Reducing the Risk of Dementia through Deprescribing (R2D2): Study Protocol for a Randomized Clinical Trial.Research square · 2024Article
- Factors Important to Older Adults Who Disagree With a Deprescribing Recommendation.JAMA network open · 2023Article
- Automatic Detection of Adverse Drug Events in Geriatric Care: Study Proposal.JMIR research protocols · 2022Article
- Assessment of Potentially Inappropriate Medications Using the EU (7)-PIM List, in a Sample of Portuguese Older Adults' Residents in Nursing Homes.Risk management and healthcare policy · 2022Article
- Organization factors influencing nurse ability to prevent and detect adverse drug events in public hospitals using a patient safety model.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021Article
- Discharge Communication of Dementia-Related Neuropsychiatric Symptoms and Care Management Strategies During Hospital to Skilled Nursing Facility Transitions.Journal of geriatric psychiatry and neurology · 2021Article
- Assessment of Patient-Preferred Language to Achieve Goal-Aligned Deprescribing in Older Adults.JAMA network open · 2021Article
- PRN Medicines Management for Older People with Long-Term Mental Health Disorders in Home Care.Risk management and healthcare policy · 2021Review
- Effect of Age on Efficacy and Safety of Fluticasone Furoate/Vilanterol (FF/VI), Umeclidinium (UMEC), and UMEC + FF/VI in Patients with Chronic Obstructive Pulmonary Disease: Analyses of Five Randomized Clinical Trials.International journal of chronic obstructive pulmonary disease · 2021Article
- Optimising medication management during the COVID-19 pandemic.Journal of pharmacy practice and research : official journal of the Society of Hospital Pharmacists of Australia · 2020Article
- Article
- Potentially inappropriate medications in community-dwelling older adults undertaken as a comprehensive geriatric risk assessment.European journal of clinical pharmacology · 2018Article
- Feasibility of Integrating Residential Care Pharmacists into Aged Care Homes to Improve Quality Use of Medicines: Study Protocol for a Non-Randomised Controlled Pilot Trial.International journal of environmental research and public health · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Appropriate prescribing for older adults presents unique challenges to the prescriber. An understanding of the scale of the problems and contributing factors is essential when designing interventions to improve patient safety. The altered pharmacology of ageing, the existence of multiple medical conditions and the exclusion of elderly patients from many trials render this subgroup of the population particularly vulnerable to underprescribing and overprescribing. Adverse drug events are common, causing significant morbidity and mortality as well as having economic implications. 'High-risk' medications such as opioids, anticoagulants and antipsychotics can have benefits in this group of patients but strategies to optimize their safety are required. Tools exist that help to identify those at risk of adverse drug reactions and to screen for inappropriate prescribing. Developments in information technology are ongoing, and it is hoped that these may enhance the process of medication reconciliation across healthcare transitions and alert the prescriber to potential adverse drug events. This review addresses commonly encountered issues when prescribing for older people, considers strategies to improve medication safety and offers a list of 'top tips' to aid the clinician.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.