Evidence map›Paper›PMID 25083173›Full record

ReviewInternational journal of fertility & sterility2014

Some reflections on intracytoplasmic morphologically selected sperm injection.

Thomas Ebner, Omar Shebl, Peter Oppelt, Richard Bernhard Mayer

Abstract readReview
In one paragraph

Review in International journal of fertility & sterility, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas EbnerDepartment of Gynecological Endocrinology and Kinderwunsch Zentrum, Landes-Frauen-and Kinderklinik and Faculty of Medicine, Johannes Kepler University, Linz, Upper Austria, Austria.
Omar SheblDepartment of Gynecological Endocrinology and Kinderwunsch Zentrum, Landes-Frauen-and Kinderklinik and Faculty of Medicine, Johannes Kepler University, Linz, Upper Austria, Austria.
Peter OppeltDepartment of Gynecological Endocrinology and Kinderwunsch Zentrum, Landes-Frauen-and Kinderklinik and Faculty of Medicine, Johannes Kepler University, Linz, Upper Austria, Austria.
Richard Bernhard MayerDepartment of Gynecological Endocrinology and Kinderwunsch Zentrum, Landes-Frauen-and Kinderklinik and Faculty of Medicine, Johannes Kepler University, Linz, Upper Austria, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although intracytoplasmic sperm injection (ICSI) allows proper fertilization in most cases of male sub fertility, it is one of the most unphysiological techniques in assisted reproductive technologies (ART). Thus, over the last decade, researchers have tried to improve sperm observation with higher-resolution microscopy techniques such as the intracytoplasmic morphologically selected sperm injection (IMSI) technique. In order to identify literatures for this review, the PubMed database was searched from 2000 onwards using the terms IMSI, motile sperm organelle morphology examination (MSOME) and sperm vacuole. Approximately 10 years after the introduction of the MSOME and IMSI procedures, several questions related to the prevalence, origin, location, and clinical consequences of sperm vacuoles have not yet been clarified. It seems that IMSI as a routine application is not state of the art and the only confirmed indications for IMSI are recurrent implantation failure following ICSI and severe male factor.

Indexed as

ChromatinDNAICSISperm HeadVacuole

Identifiers

PMID25083173
PMCPMC4107682

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.