Evidence map›Paper›PMID 25083070›Full record

ReviewWorld journal of gastroenterology2014

Natural products and food components with anti-Helicobacter pylori activities.

Hiroaki Takeuchi, Vu Thu Trang, Norihito Morimoto, Yoshie Nishida, Yoshihisa Matsumura, Tetsuro Sugiura

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Beyond Antibiotics: Alternative Strategies TargetingExpert reviews in molecular medicine · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. A review for non-antibiotic treatment ofFrontiers in microbiology · 2024
    Review
  11. The effects and mechanisms of natural products onFrontiers in cellular and infection microbiology · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Efficacy of Qingre Huashi decoction on infection of : inhibiting adhesion, antioxidant, and anti-inflammation.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2022
    Article
  16. Incorporation ofFoods (Basel, Switzerland) · 2022
    Article
  17. Plant-Based Polyphenols: Anti-Antioxidants (Basel, Switzerland) · 2022
    Review
  18. International journal of microbiology · 2022
    Article
  19. Article
  20. Fighting the Antibiotic Crisis: Flavonoids as Promising Antibacterial Drugs AgainstFrontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroaki TakeuchiHiroaki Takeuchi, Norihito Morimoto, Yoshie Nishida, Yoshihisa Matsumura, Tetsuro Sugiura, Department of Clinical Laboratory Medicine, Kochi Medical School, Kochi 783-8505, Japan.
Vu Thu TrangHiroaki Takeuchi, Norihito Morimoto, Yoshie Nishida, Yoshihisa Matsumura, Tetsuro Sugiura, Department of Clinical Laboratory Medicine, Kochi Medical School, Kochi 783-8505, Japan.
Norihito MorimotoHiroaki Takeuchi, Norihito Morimoto, Yoshie Nishida, Yoshihisa Matsumura, Tetsuro Sugiura, Department of Clinical Laboratory Medicine, Kochi Medical School, Kochi 783-8505, Japan.
Yoshie NishidaHiroaki Takeuchi, Norihito Morimoto, Yoshie Nishida, Yoshihisa Matsumura, Tetsuro Sugiura, Department of Clinical Laboratory Medicine, Kochi Medical School, Kochi 783-8505, Japan.
Yoshihisa MatsumuraHiroaki Takeuchi, Norihito Morimoto, Yoshie Nishida, Yoshihisa Matsumura, Tetsuro Sugiura, Department of Clinical Laboratory Medicine, Kochi Medical School, Kochi 783-8505, Japan.
Tetsuro SugiuraHiroaki Takeuchi, Norihito Morimoto, Yoshie Nishida, Yoshihisa Matsumura, Tetsuro Sugiura, Department of Clinical Laboratory Medicine, Kochi Medical School, Kochi 783-8505, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bacterial pathogen Helicobacter pylori (H. pylori) colonizes in over half of the world's population. H. pylori that establishes life-long infection in the stomach is definitely associated with gastro-duodenal diseases and a wide variety of non-gastrointestinal tract conditions such as immune thrombocytopenia. Triple therapy which consists of a proton pump inhibitor and combinations of two antibiotics (amoxicillin, clarithromycin or amoxicillin, metronidazol) is commonly used for H. pylori eradication. Recently, the occurrence of drug-resistant H. pylori and the adverse effect of antibiotics have severely weakened eradication therapy. Generally antibiotics induce the disturbance of human gastrointestinal microflora. Furthermore, there are inappropriate cases of triple therapy such as allergy to antibiotics, severe complications (liver and/or kidney dysfunction), the aged and people who reject the triple therapy. These prompt us to seek alterative agents instead of antibiotics and to develop more effective and safe therapy with these agents. The combination of these agents actually may result in lower a dose of antibiotics. There are many reports world-wide that non-antibiotic substances from natural products potentially have an anti-H. pylori agent. We briefly review the constituents derived from nature that fight against H. pylori in the literature with our studies.

Indexed as

Dietary SupplementsAnimalsAnti-Bacterial AgentsComplementary TherapiesDrug Resistance, BacterialDrug Therapy, CombinationGastrointestinal AgentsHelicobacter InfectionsHelicobacter pyloriHumansPhytotherapyPlant ExtractsPlants, MedicinalProton Pump InhibitorsTreatment OutcomeAnti-Bacterial AgentsGastrointestinal AgentsPlant ExtractsProton Pump InhibitorsAnti-Helicobacter pylori effectCombined effectFood componentHelicobacter pylori treatmentHuman healthIn vitro and in vivo effectsNatural product

Identifiers

PMID25083070
PMCPMC4112882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.