Evidence map›Paper›PMID 25082694›Full record

ArticleScience (New York, N.Y.)2014

Transcription. Comment on "Mechanism of eukaryotic RNA polymerase III transcription termination".

Aneeshkumar G Arimbasseri, George A Kassavetis, Richard J Maraia

Abstract readComment
In one paragraph

Article in Science (New York, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Regulation of Transcript Elongation.Annual review of microbiology · 2015
    Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Aneeshkumar G ArimbasseriIntramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
George A KassavetisDivision of Biological Sciences, University of California, San Diego, CA, USA.
Richard J MaraiaIntramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA. Commissioned Corps, U.S. Public Health Service. maraiar@mail.nih.gov.

Funding

Molecular Regulation Of RNA MetabolismZIAHD000412 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MARAIA, RICHARD J · 2009 to 2025
$31.6M
Intramural NIH HHS Z99 HD999999Intramural NIH HHS ZIA HD000412
6 · The paper itself

Abstract

Nielsen et al. (Reports, 28 June 2013, p. 1577) characterized their RNA polymerase III (Pol III) preparation and concluded that it requires an RNA hairpin/duplex structure for terminating transcription. We could not corroborate their findings using bona fide Pol III from two laboratory sources. We show that Pol III efficiently terminates transcription in the absence of a hairpin/duplex in vitro and in vivo.

Indexed as

Transcription Termination, GeneticRNA Polymerase IIISaccharomyces cerevisiaeRNA Polymerase III

Identifiers

PMID25082694
PMCPMC4157655

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.