ArticleScientific reports2014
Type 2C protein phosphatase is a key regulator of antiviral extreme resistance limiting virus spread.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 63 citations in OpenAlex.
- Signaling Pathway Analysis and Downstream Genes Associated with Disease Resistance Mediated byPlants (Basel, Switzerland) · 2026Article
- MutMap-Based Cloning of a Soybean Mosaic Virus Resistance Gene.Plants (Basel, Switzerland) · 2025Article
- Phosphatases: Decoding the Role of Mycorrhizal Fungi in Plant Disease Resistance.International journal of molecular sciences · 2024Review
- WGCNA Reveals Hub Genes and Key Gene Regulatory Pathways of the Response of Soybean to Infection byGenes · 2024Article
- A plant NLR receptor employs ABA central regulator PP2C-SnRK2 to activate antiviral immunity.Nature communications · 2024Article
- Genetic and molecular analysis of stem rot (Sclerotinia sclerotiorum) resistance in Brassica napus (canola type).Heliyon · 2023Article
- Viral synergism suppresses R gene-mediated resistance by impairing downstream defense mechanisms in soybean.Plant physiology · 2023Article
- Review
- Binding immunoglobulin 2 functions as a proviral factor for potyvirus infections in Nicotiana benthamiana.Molecular plant pathology · 2023Article
- Transcriptome analysis of two tobacco varieties with contrast resistance toFrontiers in plant science · 2023Article
- Overexpression of a Cinnamyl Alcohol Dehydrogenase-Coding Gene,International journal of molecular sciences · 2022Article
- Photosynthesis-related genes induce resistance against soybean mosaic virus: Evidence for involvement of the RNA silencing pathway.Molecular plant pathology · 2022Article
- Dynamic Transcriptome Profiling of Mungbean Genotypes Unveil the Genes Respond to the Infection of Mungbean Yellow Mosaic Virus.Pathogens (Basel, Switzerland) · 2022Article
- Insight into aphid mediatedFrontiers in microbiology · 2022Review
- Current understanding of the interplays between host hormones and plant viral infections.PLoS pathogens · 2021Review
- Extreme Resistance to Viruses in Potato and Soybean.Frontiers in plant science · 2021Review
- Abscisic Acid Connects Phytohormone Signaling with RNA Metabolic Pathways and Promotes an Antiviral Response that Is Evaded by a Self-Controlled RNA Virus.Plant communications · 2020Article
- Involvement of the chloroplast gene ferredoxin 1 in multiple responses of Nicotiana benthamiana to Potato virus X infection.Journal of experimental botany · 2020Article
- Plant Molecular Responses to Potato Virus Y: A Continuum of Outcomes from Sensitivity and Tolerance to Resistance.Viruses · 2020Review
- Soybean Resistance to Soybean Mosaic Virus.Plants (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effector-triggered immunity (ETI) is an active immune response triggered by interactions between host resistance proteins and their cognate effectors. Although ETI is often associated with the hypersensitive response (HR), various R genes mediate an HR-independent process known as extreme resistance (ER). In the soybean-Soybean mosaic virus (SMV) pathosystem, the strain-specific CI protein of SMV functions as an effector of Rsv3-mediated ER. In this study, we used the soybean (Rsv3)-SMV (CI) pathosystem to gain insight into the molecular signaling pathway involved in ER. We used genome-wide transcriptome analysis to identify a subset of the type 2C protein phophatase (PP2C) genes that are specifically up-regulated in Rsv3-mediated ER. Gain-of-function analysis of the most significantly expressed soybean PP2C gene, GmPP2C3a, showed that ABA-induced GmPP2C3a functions as a key regulator of Rsv3-mediated ER. Our results further suggest that the primary mechanism of ER against viruses is the inhibition of viral cell-to-cell movement by callose deposition in an ABA signaling-dependent manner.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.