ArticleBMC plant biology2014
Cadmium-induced ethylene production and responses in Arabidopsis thaliana rely on ACS2 and ACS6 gene expression.
Article in BMC plant biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed, 194 citations in OpenAlex.
- Plant Responses to Heavy Metal Stress: Molecular Mechanisms, Transcriptomic Regulation, and Multi-Omics Integration in Crop Improvement.Plants (Basel, Switzerland) · 2026Review
- Integrative transcriptional regulatory networks governing cereal root responses to heavy metals and drought.Plant cell reports · 2026Review
- SlALKBH9B is involved in drought-induced flower drop by regulating ethylene production.Horticulture research · 2025Article
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- Spatiotemporal transcriptome and metabolome landscapes of cotton fiber during initiation and early development.Nature communications · 2025Article
- An Overview of the Mechanisms through Which Plants Regulate ROS Homeostasis under Cadmium Stress.Antioxidants (Basel, Switzerland) · 2024Review
- RsRbohD1 Plays a Significant Role in ROS Production during Radish Pithiness Development.Plants (Basel, Switzerland) · 2024Article
- Profiling of 1-aminocyclopropane-1-carboxylic acid and selected phytohormones in Arabidopsis using liquid chromatography-tandem mass spectrometry.Plant methods · 2024Article
- The Ethylene Biosynthetic Enzymes, 1-Aminocyclopropane-1-Carboxylate (ACC) Synthase (ACS) and ACC Oxidase (ACO): The Less Explored Players in Abiotic Stress Tolerance.Biomolecules · 2024Review
- Genome-Wide Identification and Expression Analysis of 1-Aminocyclopropane-1-Carboxylate Synthase (Plants (Basel, Switzerland) · 2023Article
- The TabHLH094-TaMYC8 complex mediates the cadmium response in wheat.Molecular breeding : new strategies in plant improvement · 2023Article
- The Effect of Cadmium on Plants in Terms of the Response of Gene Expression Level and Activity.Plants (Basel, Switzerland) · 2023Review
- The Early Oxidative Stress Induced by Mercury and Cadmium Is Modulated by Ethylene inAntioxidants (Basel, Switzerland) · 2023Article
- Endophytic yeast protect plants against metal toxicity by inhibiting plant metal uptake through an ethylene-dependent mechanism.Plant, cell & environment · 2023Article
- Chromosome-level reference genome of tetraploid Isoetes sinensis provides insights into evolution and adaption of lycophytes.GigaScience · 2022Article
- Physio-Biochemical and Transcriptomic Features of Arbuscular Mycorrhizal Fungi Relieving Cadmium Stress in Wheat.Antioxidants (Basel, Switzerland) · 2022Article
- Overexpression ofCells · 2022Article
- Global leaf and root transcriptome in response to cadmium reveals tolerance mechanisms in Arundo donax L.BMC genomics · 2022Article
- Helping plants to deal with heavy metal stress: the role of nanotechnology and plant growth promoting rhizobacteria in the process of phytoremediation.Environmental science and pollution research international · 2022Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnthropogenic activities cause metal pollution worldwide. Plants can absorb and accumulate these metals through their root system, inducing stress as a result of excess metal concentrations inside the plant. Ethylene is a regulator of multiple plant processes, and is affected by many biotic and abiotic stresses. Increased ethylene levels have been observed after exposure to excess metals but it remains unclear how the increased ethylene levels are achieved at the molecular level. In this study, the effects of cadmium (Cd) exposure on the production of ethylene and its precursor 1-aminocyclopropane-1-carboxylic acid (ACC), and on the expression of the ACC Synthase (ACS) and ACC Oxidase (ACO) multigene families were investigated in Arabidopsis thaliana.
resultsIncreased ethylene release after Cd exposure was directly measurable in a system using rockwool-cultivated plants; enhanced levels of the ethylene precursor ACC together with higher mRNA levels of ethylene responsive genes: ACO2, ETR2 and ERF1 also indicated increased ethylene production in hydroponic culture. Regarding underlying mechanisms, it was found that the transcript levels of ACO2 and ACO4, the most abundantly expressed members of the ACO multigene family, were increased upon Cd exposure. ACC synthesis is the rate-limiting step in ethylene biosynthesis, and transcript levels of both ACS2 and ACS6 showed the highest increase and became the most abundant isoforms after Cd exposure, suggesting their importance in the Cd-induced increase of ethylene production.
conclusionsCadmium induced the biosynthesis of ACC and ethylene in Arabidopsis thaliana plants mainly via the increased expression of ACS2 and ACS6. This was confirmed in the acs2-1acs6-1 double knockout mutants, which showed a decreased ethylene production, positively affecting leaf biomass and resulting in a delayed induction of ethylene responsive gene expressions without significant differences in Cd contents between wild-type and mutant plants.
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