ReviewProgress in molecular biology and translational science2014
Mechanical force sensing in tissues.
Review in Progress in molecular biology and translational science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed.
- Using tunable hydrogel microparticles to measure cellular forces.Nature protocols · 2026Review
- Temporal Stretch-Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Highly transparent elastic optical microcavities for interferometric mapping of cell mechanics.Biomedical optics express · 2025Article
- A subset of transposable elements as mechano-response enhancer elements in controlling human embryonic stem cell fate.Nature cell biology · 2025Article
- Mechanisms and Therapeutic Strategies for Minority Cell-Induced Paclitaxel Resistance and Tumor Progression Mediated by Mechanical Forces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Advancing Neuroscience and Therapy: Insights into Genetic and Non-Genetic Neuromodulation Approaches.Cells · 2025Review
- Polymer design of microwell hydrogels influences epithelial-mesenchymal interactions during human bronchosphere formation.Advanced nanobiomed research · 2025Article
- Peeking into the future: inferring mechanics in dynamical tissues.Biochemical Society transactions · 2024Review
- Shear stress-stimulated AMPK couples endothelial cell mechanics, metabolism and vasodilation.Journal of cell science · 2024Article
- Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit.Nature communications · 2024Article
- Mechanical activation of VE-cadherin stimulates AMPK to increase endothelial cell metabolism and vasodilation.bioRxiv : the preprint server for biology · 2024Article
- A Hierarchical Mechanotransduction System: From Macro to Micro.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- The mechanics of cephalic furrow formation in the Drosophila embryo.Biophysical journal · 2023Article
- Colorectal Cancer Cell Invasion and Functional Properties Depend on Peri-Tumoral Extracellular Matrix.Biomedicines · 2023Article
- Vinculin Y822 is an important determinant of ligand binding.Journal of cell science · 2023Article
- Functional maturation of kidney organoid tubules: PIEZO1-mediated CaAmerican journal of physiology. Cell physiology · 2023Article
- Cell shape anisotropy contributes to self-organized feather pattern fidelity in birds.PLoS biology · 2022Article
- Force-generating apoptotic cells orchestrate avian neural tube bending.Developmental cell · 2022Article
- Optogenetic inhibition of actomyosin reveals mechanical bistability of the mesoderm epithelium duringeLife · 2022Article
- Generation, Transmission, and Regulation of Mechanical Forces in Embryonic Morphogenesis.Small (Weinheim an der Bergstrasse, Germany) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Tissue size, shape, and organization reflect individual cell behaviors such as proliferation, shape change, and movement. Evidence suggests that mechanical signals operate in tandem with biochemical cues to properly coordinate cell behavior and pattern tissues. The objective of this chapter is to present recent evidence demonstrating that forces transmitted between cells act as signals that coordinate cell behavior across tissues. We first briefly summarize molecular and cellular mechanisms by which forces are sensed by cells with an emphasis on forces generated and transmitted by cytoskeletal networks. We then discuss evidence for these mechanisms operating in multicellular contexts to coordinate complex cell and tissue behaviors that occur during embryonic development: specifically growth and morphogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.