ArticleExtremophiles : life under extreme conditions2014
The ice-binding proteins of a snow alga, Chloromonas brevispina: probable acquisition by horizontal gene transfer.
Article in Extremophiles : life under extreme conditions, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 72 citations in OpenAlex.
- A horizontally transferred bacterial gene aids the freezing tolerance of Antarctic bdelloid rotifers.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Lessons from Extremophiles: Functional Adaptations and Genomic Innovations across the Eukaryotic Tree of Life.Genome biology and evolution · 2024Article
- Polyproline type II helical antifreeze proteins are widespread in Collembola and likely originated over 400 million years ago in the Ordovician Period.Scientific reports · 2023Article
- Glaciers as microbial habitats: current knowledge and implication.Journal of microbiology (Seoul, Korea) · 2022Review
- Diatoms and Their Microbiomes in Complex and Changing Polar Oceans.Frontiers in microbiology · 2022Review
- Identification of Biomolecules Involved in the Adaptation to the Environment of Cold-Loving Microorganisms and Metabolic Pathways for Their Production.Biomolecules · 2021Review
- Ice-Binding Proteins Associated with an Antarctic Cyanobacterium,Applied and environmental microbiology · 2021Article
- Snow and Glacial Algae: A ReviewJournal of phycology · 2020Review
- Cold Adaptation Mechanisms of a Snow AlgaFrontiers in microbiology · 2020Article
- Ice-Binding Proteins in a Chrysophycean Snow Alga: Acquisition of an Essential Gene by Horizontal Gene Transfer.Frontiers in microbiology · 2019Article
- Core genes in diverse dinoflagellate lineages include a wealth of conserved dark genes with unknown functions.Scientific reports · 2018Article
- Antarctic yeasts: analysis of their freeze-thaw tolerance and production of antifreeze proteins, fatty acids and ergosterol.BMC microbiology · 2018Article
- Ecology, cytology and phylogeny of the snow algaPhycologia · 2018Article
- Structure and application of antifreeze proteins from Antarctic bacteria.Microbial cell factories · 2017Article
- Multiple ice-binding proteins of probable prokaryotic origin in an Antarctic lake alga, Chlamydomonas sp. ICE-MDV (Chlorophyceae).Journal of phycology · 2017Article
- Putting life on ice: bacteria that bind to frozen water.Journal of the Royal Society, Interface · 2016Article
- Ecophysiology, secondary pigments and ultrastructure of Chlainomonas sp. (Chlorophyta) from the European Alps compared with Chlamydomonas nivalis forming red snow.FEMS microbiology ecology · 2016Article
- Airborne Microalgae: Insights, Opportunities, and Challenges.Applied and environmental microbiology · 2016Review
- New Cysteine-Rich Ice-Binding Protein Secreted from Antarctic Microalga, Chloromonas sp.PloS one · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
All ice-and snow-related unicellular algae examined so far secrete ice-binding proteins (IBPs) to mitigate freezing damage. Two types of IBP have been identified in chlorophytes. Type 1 IBPs are members of a large family of proteins that share a large domain of unknown function (DUF3494). Previous studies have suggested that the type 1 algal IBP genes were acquired by horizontal gene transfer. To test this hypothesis I sequenced the IBP genes of a snow alga, Chloromonas brevispina. The IBPs were identified by ice affinity purification, de novo sequencing of a tryptic peptide and large-scale sequencing of the transcriptome and genome. C. brevispina has genes for over 20 IBP isoforms, which strongly indicates their importance. The IBPs are all of type 1 and match fungal and bacterial proteins more closely than they match known algal IBPs, providing further evidence that the genes were acquired by horizontal transfer. Modeling of the 3D structures of the IBPs based on the known structure of a homologous protein suggests that the ice-binding site has characteristics that are shared by all DUF3494 proteins.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.