Evidence map›Paper›PMID 25081385›Full record

ReviewAnnals of biomedical engineering2014

Cardiac tissue structure, properties, and performance: a materials science perspective.

Mark Golob, Richard L Moss, Naomi C Chesler

Abstract readReview
In one paragraph

Review in Annals of biomedical engineering, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
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  13. Exploring cardiac form and function: A length-scale computational biology approach.Wiley interdisciplinary reviews. Systems biology and medicine · 2020
    Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mark GolobDepartment of Biomedical Engineering, UW-Madison College of Engineering, 2146 Engineering Centers Building, 1550 Engineering Drive, Madison, WI, 53706, USA.
Richard L Moss
Naomi C Chesler

Funding

My-BP-C Modulation of Cardiac ContractionR37HL082900 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MOSS, RICHARD L · 2006 to 2015
$6.0M
Vascular collagen accumulation & mechanical mechanisms in pulmonary hypertensionR01HL086939 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI CHESLER, NAOMI C · 2007 to 2016
$3.6M
NHLBI NIH HHS 1R01HL086939NHLBI NIH HHS 1R37HL82900NHLBI NIH HHS R01 HL086939NHLBI NIH HHS R37 HL082900
6 · The paper itself

Abstract

From an engineering perspective, many forms of heart disease can be thought of as a reduction in biomaterial performance, in which the biomaterial is the tissue comprising the ventricular wall. In materials science, the structure and properties of a material are recognized to be interconnected with performance. In addition, for most measurements of structure, properties, and performance, some processing is required. Here, we review the current state of knowledge regarding cardiac tissue structure, properties, and performance as well as the processing steps taken to acquire those measurements. Understanding the impact of these factors and their interactions may enhance our understanding of heart function and heart failure. We also review design considerations for cardiac tissue property and performance measurements because, to date, most data on cardiac tissue has been obtained under non-physiological loading conditions. Novel measurement systems that account for these design considerations may improve future experiments and lead to greater insight into cardiac tissue structure, properties, and ultimately performance.

Indexed as

AnimalsBiomechanical PhenomenaHeartHeart FailureHumansModels, BiologicalSarcomeres

Identifiers

PMID25081385
PMCPMC4177091

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.