ArticleEndocrine2014
Cons: endoscopic endonasal transsphenoidal pituitary surgery is not superior to microscopic transsphenoidal surgery for pituitary adenomas.
Article in Endocrine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Safety and efficacy of endoscopic vs. microscopic approaches in pituitary adenoma surgery: A systematic review and meta-analysis.Neurosurgical review · 2025Pooled it
- Gross total resection of pituitary adenomas after endoscopic vs. microscopic transsphenoidal surgery: a meta-analysis.Acta neurochirurgica · 2018Pooled it
- Comparison of endoscopic and endoscope-assisted microscopic transsphenoidal surgery for pituitary adenoma resection: a prospective randomized study.Frontiers in endocrinology · 2025Trial
- Sinonasal Symptoms and Self-Reported Health before and after Endoscopic Pituitary Surgery-A Prospective Study.Journal of neurological surgery. Part B, Skull base · 2022Article
- 4K 3-dimensional video microscope system (orbeye) for transsphenoidal pituitary surgery.Acta neurochirurgica · 2021Observational
- Endoscopic versus nonendoscopic surgery for resection of pituitary adenomas: a national database study.Journal of neurosurgery · 2021Article
- "NIMS" nasal mucoperiosteal flap for sublabial trans-sphenoidal surgical defect repair: A new technique under microscope.Surgical neurology international · 2021Article
- The optimal numerosity of the referral population of pituitary tumors centers of excellence (PTCOE): A surgical perspective.Reviews in endocrine & metabolic disorders · 2020Review
- The IDEAL framework in neurosurgery: a bibliometric analysis.Acta neurochirurgica · 2020Review
- Residual Tumor Confers a 10-Fold Increased Risk of Regrowth in Clinically Nonfunctioning Pituitary Tumors.Journal of the Endocrine Society · 2019Article
- Pituitary adenomas in elderly patients: clinical and surgical outcome analysis in a large series.Endocrine · 2019Article
- A study on sublabial transsphenoidal treatment of pituitary tumor under microscope with aid of endoscope.Chinese neurosurgical journal · 2018Article
- Microsurgical therapy of pituitary adenomas.Endocrine · 2018Article
- Safety of transsphenoidal microsurgical approach in patients with an ACTH-secreting pituitary adenoma.Endocrine · 2017Article
- Recent Evolution of Endoscopic Endonasal Surgery for Treatment of Pituitary Adenomas.Neurologia medico-chirurgica · 2017Review
- Microscopic surgery for pituitary adenomas to preserve the pituitary gland and stalk.Experimental and therapeutic medicine · 2017Article
- The surgical treatment of acromegaly.Pituitary · 2017Review
- Parasellar Extension Grades and Surgical Extent in Endoscopic Endonasal Transsphenoidal Surgery for Pituitary Adenomas : A Single Surgeon's Consecutive Series with the Aspects of Reliability and Clinical Validity.Journal of Korean Neurosurgical Society · 2016Article
- Review
- Optimal use of pegvisomant in acromegaly: are we getting there?Endocrine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The introduction of the endoscope to transsphenoidal pituitary surgery is not new and it has been abandoned in the past. Now, after some technological advances has been proposed again as an advancement in this field. However, there is still a debate on this topic and some authors consider endoscopic surgery a form of developing surgery in an evolution step. The use of the endoscope to visualize the sella has been suggested to offer a better visualization as well as an improved range of motion compared to the operating microscope. However, the real advantage in terms of efficacy and safety is still matter of debate. The conversion to microsurgery has been reported in a significant number of cases, particularly in recurrences, where the difficulties of reoperation require more skill. There is evidence in recent studies that the endonasal and bleeding complications are significantly higher in endoscopic approaches than in microscopic ones. In particular, patient discomfort, smell, and taste impairment are higher with the endoscopic method compared with microscopic approaches. At present pure endoscopic transsphenoidal surgery is not a cost effective technology. In fact, the operative time is longer than in microscopic approaches and the number of surgeons required for the procedure is usually double compared to microscopic approaches. This paper will outline on the basis of the data available in literature the reasons why, at present, the pure endoscopic endonasal transsphenoidal surgery should not be yet considered the standard technique for transsphenoidal surgery in patients with pituitary adenomas.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.