Trial reportAmerican journal of epidemiology2014
An updated natural history model of cervical cancer: derivation of model parameters.
Trial report in American journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00342173 (Costa Rican Natural History Study of HPV and Cervical Neoplasia), which is not on this map. Cited by 68 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Costa Rican Natural History Study of HPV and Cervical Neoplasia
Who cites it
68 citing papers in PubMed.
- Adapting Sexual Behavior Survey Data to Parameterize an Agent-Based Model of Human Papillomavirus (HPV) Transmission.Medical decision making : an international journal of the Society for Medical Decision Making · 2026Article
- Mock Samples That Mimic Human Cervicovaginal Samples to Accelerate the Development and Evaluation of Assays for High-Risk HPV for Cervical Cancer Screening.Journal of medical virology · 2026Article
- Discrete-Event Simulation Modeling Framework for Cancer Interventions and Population Health in R (DESCIPHR): An Open-Source Pipeline.PharmacoEconomics · 2026Article
- Cost-effectiveness of HPV catch-up vaccination program in women aged 13-24 years in a middle income country.Journal of gynecologic oncology · 2026Article
- A Scoping Review on Calibration Methods for Cancer Simulation Models.Medical decision making : an international journal of the Society for Medical Decision Making · 2025Article
- Review
- Extraction-free RT-RPA assay for detection of HPV16, HPV18, and HPV45 mRNA expression.Scientific reports · 2025Article
- Advances in HPV-Associated Cervical Cancer Dynamic Modelling for Prevention and Control Evaluation.China CDC weekly · 2025Article
- Cost-effectiveness analysis of single-dose or 2-dose of bivalent, quadrivalent, or nonavalent HPV vaccine in a low/middle-income country setting.Journal of gynecologic oncology · 2024Article
- Population-level health impact of hypothetical waning 1-dose human papillomavirus vaccination and 2-dose mitigation strategies in a high cervical cancer burden setting.Journal of the National Cancer Institute. Monographs · 2024Article
- Efficacy and Safety of 5-Aminolevulinic Acid Photodynamic Therapy for Treating Cervical and Vaginal Intraepithelial Neoplasia.Pharmaceutics · 2024Article
- The impact of alternate HPV vaccination and cervical screening strategies in Japan: a cost-effectiveness analysis.The Lancet regional health. Western Pacific · 2024Article
- Unraveling cervical cancer screening dilemmas: histopathological insights from VIA and LEEP at bugando medical centre, Mwanza.BMC cancer · 2024Article
- Adapting a model of cervical carcinogenesis to self-identified Black women to evaluate racial disparities in the United States.Journal of the National Cancer Institute. Monographs · 2023Article
- Global impact and cost-effectiveness of one-dose versus two-dose human papillomavirus vaccination schedules: a comparative modelling analysis.BMC medicine · 2023Article
- Cost-effectiveness of artificial intelligence-assisted liquid-based cytology testing for cervical cancer screening in China.The Lancet regional health. Western Pacific · 2023Article
- Cervical Microbiota Influences Cytokine Diversity in Cervical Intraepithelial Neoplasia among Rural Women in the Akyemansa District of Ghana.BioMed research international · 2023Article
- Now or later: Health impacts of delaying single-dose HPV vaccine implementation in a high-burden setting.International journal of cancer · 2022Article
- Association between common vaginal and HPV infections and results of cytology test in the Zhoupu District, Shanghai City, China, from 2014 to 2019.Virology journal · 2022Article
- Potential effectiveness of a therapeutic HPV intervention campaign in Uganda.International journal of cancer · 2022Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Mathematical models of cervical cancer have been widely used to evaluate the comparative effectiveness and cost-effectiveness of preventive strategies. Major advances in the understanding of cervical carcinogenesis motivate the creation of a new disease paradigm in such models. To keep pace with the most recent evidence, we updated a previously developed microsimulation model of human papillomavirus (HPV) infection and cervical cancer to reflect 1) a shift towards health states based on HPV rather than poorly reproducible histological diagnoses and 2) HPV clearance and progression to precancer as a function of infection duration and genotype, as derived from the control arm of the Costa Rica Vaccine Trial (2004-2010). The model was calibrated leveraging empirical data from the New Mexico Surveillance, Epidemiology, and End Results Registry (1980-1999) and a state-of-the-art cervical cancer screening registry in New Mexico (2007-2009). The calibrated model had good correspondence with data on genotype- and age-specific HPV prevalence, genotype frequency in precancer and cancer, and age-specific cancer incidence. We present this model in response to a call for new natural history models of cervical cancer intended for decision analysis and economic evaluation at a time when global cervical cancer prevention policy continues to evolve and evidence of the long-term health effects of cervical interventions remains critical.
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