Evidence map›Paper›PMID 25080879›Full record

ReviewCellular and molecular life sciences : CMLS2014

Common and unique features of viral RNA-dependent polymerases.

Aartjan J W te Velthuis

Open access · hybridAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 157 papers.

0numbers the graph read from it
0cells of the map it votes in
157citing papers in PubMed
16.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

157 citing papers in PubMed, 271 citations in OpenAlex.

  1. Trial
  2. Diversity of Antarctic sea ice and under-ice seawater RNA viruses.Applied and environmental microbiology · 2026
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  13. Mycoviruses confer hypovirulence but enhance antifungal volatile organic compound production in a phytopathogenic fungus.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  20. Exploring the Structural Lexicon of the Proteome via Metric Geometry.bioRxiv : the preprint server for biology · 2025
    Article

97 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 2 countries.

Aartjan J W te VelthuisMolecular Virology Laboratory, Department of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands, aartjan.tevelthuis@path.ox.ac.uk.
Leiden University Medical Center · NL

Funding

Wellcome Trust 098721Wellcome Trust 098721/Z/12/Z
6 · The paper itself

Abstract

Eukaryotes and bacteria can be infected with a wide variety of RNA viruses. On average, these pathogens share little sequence similarity and use different replication and transcription strategies. Nevertheless, the members of nearly all RNA virus families depend on the activity of a virally encoded RNA-dependent polymerase for the condensation of nucleotide triphosphates. This review provides an overview of our current understanding of the viral RNA-dependent polymerase structure and the biochemistry and biophysics that is involved in replicating and transcribing the genetic material of RNA viruses.

Indexed as

Catalytic DomainDNA-Directed RNA PolymerasesPromoter Regions, GeneticProtein MultimerizationRNA, ViralRNA VirusesDNA-Directed RNA PolymerasesRNA, Viral

Identifiers

PMID25080879
PMCPMC4207942
OpenAlexW1967819126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.