ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
On the role of suppression in spatial attention: evidence from negative BOLD in human subcortical and cortical structures.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 54 citations in OpenAlex.
- Negative BOLD response to interictal discharges in epilepsy using intracranial EEG-fMRI.Neuroimage. Reports · 2026Article
- Unsupervised visual learning is revealed for task-irrelevant natural scenes due to reduced attentional suppression effects in visual areas.Nature communications · 2026Article
- The Neural Organization of Visual Information in the Auditory Cortex of the Congenitally Deaf.Human brain mapping · 2026Article
- Attention Alters Population Spatial Frequency Tuning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Investigating the Consistency of Negative BOLD Responses to Combinations of Visual, Auditory, and Somatosensory Stimuli and Their Modulation by the Level of Task Demand.Human brain mapping · 2025Article
- Distinctive and Complementary Roles of Default Mode Network Subsystems in Semantic Cognition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- The Emergence of Tuning to Global Shape Properties of Radial Frequency Patterns in the Ventral Visual Pathway.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- FMRI and intra-cranial electrocorticography recordings in the same human subjects reveals negative BOLD signal coupled with silenced neuronal activity.Brain structure & function · 2022Article
- Spatial and Feature-selective Attention Have Distinct, Interacting Effects on Population-level Tuning.Journal of cognitive neuroscience · 2022Article
- Behavioral Prioritization Enhances Working Memory Precision and Neural Population Gain.Journal of cognitive neuroscience · 2022Article
- Retinotopic variations of the negative blood-oxygen-level dependent hemodynamic response function in human primary visual cortex.Journal of neurophysiology · 2021Article
- Prior context influences motor brain areas in an auditory oddball task and prefrontal cortex multitasking modelling.Brain informatics · 2021Article
- Knowing what you need to know in advance: The neural processes underpinning flexible semantic retrieval of thematic and taxonomic relations.NeuroImage · 2021Article
- Value-driven attentional capture enhances distractor representations in early visual cortex.PLoS biology · 2019Article
- Functional MRI and EEG Index Complementary Attentional Modulations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Engagement of Pulvino-cortical Feedforward and Feedback Pathways in Cognitive Computations.Neuron · 2019Article
- Dissociable signatures of visual salience and behavioral relevance across attentional priority maps in human cortex.Journal of neurophysiology · 2018Article
- Perceptual Competition Promotes Suppression of Reward Salience in Behavioral Selection and Neural Representation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Two different mechanisms support selective attention at different phases of training.PLoS biology · 2017Article
- Learning to read alters cortico-subcortical cross-talk in the visual system of illiterates.Science advances · 2017Article
Corrections and comments
- Erratum issuedRogers, Jessica [Corrected to Rodgers, Jessica]
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is clear evidence that spatial attention increases neural responses to attended stimuli in extrastriate visual areas and, to a lesser degree, in earlier visual areas. Other evidence shows that neurons representing unattended locations can also be suppressed. However, the extent to which enhancement and suppression is observed, their stimulus dependence, and the stages of the visual system at which they are expressed remains poorly understood. Using fMRI we set out to characterize both the task and stimulus dependence of neural responses in the lateral geniculate nucleus (LGN), primary visual cortex (V1), and visual motion area (V5) in humans to determine where suppressive and facilitatory effects of spatial attention are expressed. Subjects viewed a lateralized drifting grating stimulus, presented at multiple stimulus contrasts, and performed one of three tasks designed to alter the spatial location of their attention. In retinotopic representations of the stimulus location, we observed increasing attention-dependent facilitation and decreasing dependence on stimulus contrast moving up the visual hierarchy from the LGN to V5. However, in the representations of unattended locations of the LGN and V1, we observed suppression, which was not significantly dependent on the attended stimulus contrast. These suppressive effects were also found in the pulvinar, which has been frequently associated with attention. We provide evidence, therefore, for a spatially selective suppressive mechanism that acts at a subcortical level.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.