Evidence map›Paper›PMID 25080455›Full record

ArticleThe American journal of clinical nutrition2014

Eggs as a dietary source for gut microbial production of trimethylamine-N-oxide.

Stanley L Hazen, J Mark Brown

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of clinical nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Association of diet with circulating trimethylamine-N-oxide concentration.The American journal of clinical nutrition · 2020
    Article
  18. Article
  19. Egg consumption, cardiovascular diseases and type 2 diabetes.European journal of clinical nutrition · 2018
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Stanley L HazenFrom the Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland, OH. hazens@ccf.org.
J Mark BrownFrom the Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland, OH.

Funding

Gut Flora Metabolism of Dietary Phosphatidylcholine and CVDR01HL103866 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI HAZEN, STANLEY L · 2010 to 2023
$10.8M
Functional Cardio-MetabolomicsP20HL113452 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI HAZEN, STANLEY L, TANG, WAI HONG WILSON · 2012 to 2016
$4.8M
Enzymatic Control of Trimethylamineoxide (TMAO)Induced AtherosclerosisR01HL122283 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BROWN, JONATHAN MARK · 2014 to 2018
$2.0M
NHLBI NIH HHS P20 HL113452NHLBI NIH HHS R01 HL103866NHLBI NIH HHS R01 HL122283
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Up-RegulationCholineEggsFemaleHeart DiseasesHumansMaleMethylaminesCholineMethylaminestrimethyloxamine

Identifiers

PMID25080455
PMCPMC4135484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.