ArticleChemistry (Weinheim an der Bergstrasse, Germany)2014
Gold(I)-catalysed direct thioetherifications using allylic alcohols: an experimental and computational study.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 27 citations in OpenAlex.
- B(CChemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Recent progress in the chemistry of β-aminoketones.RSC advances · 2022Review
- Rapid Iododeboronation with and without Gold Catalysis: Application to Radiolabelling of Arenes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018Article
- Chirality Transfer in Gold(I)-Catalysed Direct Allylic Etherifications of Unactivated Alcohols: Experimental and Computational Study.Chemistry (Weinheim an der Bergstrasse, Germany) · 2015Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A gold(I)-catalysed direct thioetherification reaction between allylic alcohols and thiols is presented. The reaction is generally highly regioselective (S(N)2'). This dehydrative allylation procedure is very mild and atom economical, producing only water as the by-product and avoiding any unnecessary waste/steps associated with installing a leaving or activating group on the substrate. Computational studies are presented to gain insight into the mechanism of the reaction. Calculations indicate that the regioselectivity is under equilibrium control and is ultimately dictated by the thermodynamic stability of the products.
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