Evidence map›Paper›PMID 25080290›Full record

ArticleInternational journal of STD & AIDS2015

Changes in the pattern of Kaposi's sarcoma at Ocean Road Cancer Institute in Tanzania (2006-2011).

Lia Koski, Twalib Ngoma, Julius Mwaiselage, Lynne Le, Amr S Soliman

Abstract readEvaluation Study
In one paragraph

Article in International journal of STD & AIDS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Developing Research Education Groups in African Cancer Centers: The Experience in Tanzania.Journal of cancer education : the official journal of the American Association for Cancer Education · 2021
    Article
  6. Developing and Maintaining a Global Research Training Infrastructure for Cancer Education.Journal of cancer education : the official journal of the American Association for Cancer Education · 2021
    Article
  7. Epidemiology of Kaposi's sarcoma in Zambia, 2007 - 2014.Malawi medical journal : the journal of Medical Association of Malawi · 2020
    Article
  8. Article
  9. Article
  10. Review
  11. Malignancies in women with HIV infection.Current opinion in HIV and AIDS · 2017
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lia KoskiUniversity of Michigan School of Public Health, Ann Arbor USA.
Twalib NgomaOcean Road Cancer Institute, Dar es Salaam, Tanzania.
Julius MwaiselageOcean Road Cancer Institute, Dar es Salaam, Tanzania.
Lynne LeDepartment of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA.
Amr S SolimanDepartment of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA amr.soliman@unmc.edu.

Funding

Cancer Epidemiology Education in Special Populations Program-15R25CA112383 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Amr Soliman · 2006 to 2026
$6.1M
NCI NIH HHS R25 CA112383NCI NIH HHS R25CA112383
6 · The paper itself

Abstract

Tanzania has high human immunodeficiency virus and human herpes virus-8 rates linked to Kaposi's sarcoma. We conducted a study at the Ocean Road Cancer Institute in Dar es Salaam, Tanzania to examine changes in proportions of Kaposi's sarcoma to all cancers over the period (2006-2011) of increased acquired immune deficiency syndrome management by anti-retroviral therapy. We included 1504 Kaposi's sarcoma cases from Ocean Road Cancer Institute and abstracted information regarding age, gender, human immunodeficiency virus and tuberculosis, anti-retroviral therapy duration and Kaposi's sarcoma lesions. Male Kaposi's sarcoma patients (59.6%) were older (42.1 ± 11.5 years) than women (40.4%) (36.2 ± 9.6 years). Kaposi's sarcoma proportions declined from 10.1% in 2003 to 7.4% in 2011. Being a woman was associated with increased oral and generalized lesions and higher numbers of lesion locations (odds ratio [OR] = 2.17, 95% confidence interval [CI]: 1.35, 3.51; OR = 1.49, CI: 1.08, 2.06; OR = 1.06, CI: 0.79, 1.41, respectively). Tuberculosis was associated with oral, generalized and number of lesion locations (OR = 2.08, CI: 1.10, 3.93; OR = 2.06, CI: 1.28, 3.33; OR = 1.88, CI: 1.19, 2.97, respectively). Anti-retroviral therapy duration showed a protective effect with oral, generalized and number of lesion locations (OR = 0.55, CI: 0.33, 0.91; OR = 0.73, CI: 0.52, 1.01; OR = 0.89, CI: 0.67, 1.18, respectively). With increasing number of patients receiving prolonged anti-retroviral therapy, future studies should investigate long-term effect of anti-retroviral therapy and tuberculosis in Tanzania and countries with human immunodeficiency virus infection.

Indexed as

AdultAgedAIDS-Related Opportunistic InfectionsAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveFemaleHIV InfectionsHIV SeropositivityHumansMaleMiddle AgedOdds RatioSarcoma, KaposiSocioeconomic FactorsTanzaniaTreatment OutcomeAnti-HIV AgentsAIDSantiretroviral therapycancerHHV-8HIVhuman herpes virus-8Human immunodeficiency virusKaposi’s sarcomaTanzaniatrend

Identifiers

PMID25080290
PMCPMC4312260

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.